CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-022303
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 39S ribosomal protein L16, mitochondrial 
Protein Synonyms/Alias
 L16mt; MRP-L16 
Gene Name
 MRPL16 
Gene Synonyms/Alias
 PNAS-111 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
47EDVSIPEKPKLRFIEacetylation[1]
49VSIPEKPKLRFIERAubiquitination[2]
155DHYVTPVKAGRLVVEubiquitination[2]
249WGKFYMPKRV*****ubiquitination[2]
Reference
 [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
 Component of the large subunit of mitochondrial ribosome. 
Sequence Annotation
  
Keyword
 Complete proteome; Mitochondrion; Polymorphism; Reference proteome; Ribonucleoprotein; Ribosomal protein; Transit peptide. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 251 AA 
Protein Sequence
MWRLLARASA PLLRVPLSDS WALLPASAGV KTLLPVPSFE DVSIPEKPKL RFIERAPLVP 60
KVRREPKNLS DIRGPSTEAT EFTEGNFAIL ALGGGYLHWG HFEMMRLTIN RSMDPKNMFA 120
IWRVPAPFKP ITRKSVGHRM GGGKGAIDHY VTPVKAGRLV VEMGGRCEFE EVQGFLDQVA 180
HKLPFAAKAV SRGTLEKMRK DQEERERNNQ NPWTFERIAT ANMLGIRKVL SPYDLTHKGK 240
YWGKFYMPKR V 251 
Gene Ontology
 GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
 GO:0005840; C:ribosome; IEA:UniProtKB-KW.
 GO:0019843; F:rRNA binding; IEA:InterPro.
 GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
 GO:0006412; P:translation; IEA:InterPro. 
Interpro
 IPR016180; Ribosomal_L10e/L16.
 IPR000114; Ribosomal_L16. 
Pfam
 PF00252; Ribosomal_L16 
SMART
  
PROSITE
  
PRINTS
 PR00060; RIBOSOMALL16.