CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036890
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein transport protein Sec24C 
Protein Synonyms/Alias
  
Gene Name
 SEC24C 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
245VTTNFLVKDQGNASPubiquitination[1]
270PCTSDMAKQAQVPLAubiquitination[1]
281VPLAAVIKPLARLPPubiquitination[1, 2]
519KAAECAGKLFLFHTSubiquitination[1, 2]
535PIAEAPGKLKNRDDRubiquitination[1, 2]
537AEAPGKLKNRDDRKLubiquitination[1]
551LINTDKEKTLFQPQTubiquitination[3]
626DLRRDVQKVVGFDAVubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Protein transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 975 AA 
Protein Sequence
MQISGAVAPA PPSSGLGFGP PTSLASASGS FPNSGLYGSY PQGQAPPLSQ AQGHPGIQTP 60
QRSAPSQASS FTPPASGGPR LPSMTGPLLP GQSFGGPSVS QPNHVSSPPQ ALPPGTQMTG 120
PLGPLPPMHS PQQPGYQPQQ NGSFGPARGP QSNYGGPYPA APTFGSQPGP PQPLPPKRLD 180
PDAIPSPQLS ELPPQQKTRH RIDPDAIPSP IQVIEDDRNN RGTEPFVTGV RGQVPPLVTT 240
NFLVKDQGNA SPRYIRCTSY NIPCTSDMAK QAQVPLAAVI KPLARLPPEE ASPYVVDHGE 300
SGPLRCNRCK AYMCPFMQFI EGGRRFQCCF CSCINDVPPQ YFQHLDHTGK RVDAYDRPEL 360
SLGSYEFLAT VDYCKNNKFP SPPAFIFMID VSYNAIRTGL VRLLCEELKS LLDFLPREGG 420
AEESAIRVGF VTYNKVLHFY NVKSSLAQPQ MMVVSDVADM FVPLLDGFLV NVNESRAVIT 480
SLLDQIPEMF ADTRETETVF VPVIQAGMEA LKAAECAGKL FLFHTSLPIA EAPGKLKNRD 540
DRKLINTDKE KTLFQPQTGA YQTLAKECVA QGCCVDLFLF PNQYVDVATL SVVPQLTGGS 600
VYKYASFQVE NDQERFLSDL RRDVQKVVGF DAVMRVRTST GIRAVDFFGA FYMSNTTDVE 660
LAGLDGDKTV TVEFKHDDRL NEESGALLQC ALLYTSCAGQ RRLRIHNLAL NCCTQLADLY 720
RNCETDTLIN YMAKFAYRGV LNSPVKAVRD TLITQCAQIL ACYRKNCASP SSAGQLILPE 780
CMKLLPVYLN CVLKSDVLQP GAEVTTDDRA YVRQLVTSMD VTETNVFFYP RLLPLTKSPV 840
ESTTEPPAVR ASEERLSNGD IYLLENGLNL FLWVGASVQQ GVVQSLFSVS SFSQITSGLS 900
VLPVLDNPLS KKVRGLIDSL RAQRSRYMKL TVVKQEDKME MLFKHFLVED KSLSGGASYV 960
DFLCHMHKEI RQLLS 975 
Gene Ontology
 GO:0030127; C:COPII vesicle coat; IEA:InterPro.
 GO:0005634; C:nucleus; IDA:HPA.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006888; P:ER to Golgi vesicle-mediated transport; IEA:InterPro.
 GO:0006886; P:intracellular protein transport; IEA:InterPro. 
Interpro
 IPR007123; Gelsolin_dom.
 IPR006900; Sec23/24_helical_dom.
 IPR006896; Sec23/24_trunk_dom.
 IPR012990; Sec23_24_beta_S.
 IPR002035; VWF_A.
 IPR006895; Znf_Sec23_Sec24. 
Pfam
 PF00626; Gelsolin
 PF08033; Sec23_BS
 PF04815; Sec23_helical
 PF04811; Sec23_trunk
 PF04810; zf-Sec23_Sec24 
SMART
  
PROSITE
  
PRINTS