CPLM 1.0 - Compendium of Protein Lysine Modification
Tag
Content
CPLM ID
CPLM-040103
UniProt Accession
F6QHF1_MOUSE
;
F6QHF1
Genbank Protein ID
CR974422
Genbank Nucleotide ID
Protein Name
Antigen peptide transporter 1
Protein Synonyms/Alias
Gene Name
Tap1
Gene Synonyms/Alias
Created Date
July 27, 2013
Organism
Mus musculus (Mouse)
NCBI Taxa ID
10090
Lysine Modification
Position
Peptide
Type
References
45
NEEGEAQ
K
FRQKLEE
ubiquitination
[1]
123
KAVGSSE
K
IFEYLDR
ubiquitination
[1]
Reference
[1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [
PMID: 22790023
]
Functional Description
Sequence Annotation
Keyword
Complete proteome; Reference proteome.
Sequence Source
UniProt (SWISSPROT/TrEMBL); GenBank; EMBL
Protein Length
196 AA
Protein Sequence
XGKVHQSLAV KVQESLAKST QVALEALSAM PTVRSFANEE GEAQKFRQKL EEMKTLNKKE 60
ALAYVAEVWT TSVSGMLLKV GILYLGGQLV IRGAVSSGNL VSFVLYQLQF TQAVQKAVGS 120
SEKIFEYLDR TPCSPLSGSL APSNMKGLVE FQDVSFAYPN QPKVQVLQGL TFTLHPGTVT 180
ALVGPNGSGK STVAAL 196
Gene Ontology
GO:0005739
; C:mitochondrion; IDA:MGI.
GO:0005886
; C:plasma membrane; IBA:RefGenome.
GO:0042825
; C:TAP complex; IBA:RefGenome.
GO:0005524
; F:ATP binding; IEA:InterPro.
GO:0015421
; F:oligopeptide-transporting ATPase activity; IBA:RefGenome.
GO:0042605
; F:peptide antigen binding; IBA:RefGenome.
GO:0046978
; F:TAP1 binding; IBA:RefGenome.
GO:0046979
; F:TAP2 binding; IBA:RefGenome.
GO:0046980
; F:tapasin binding; IBA:RefGenome.
GO:0006952
; P:defense response; IMP:MGI.
GO:0001916
; P:positive regulation of T cell mediated cytotoxicity; IBA:RefGenome.
Interpro
IPR017940
; ABC_transporter_type1.
IPR001140
; ABC_transptr_TM_dom.
IPR011527
; ABC_transptrTM_dom_typ1.
IPR027417
; P-loop_NTPase.
Pfam
PF00664
; ABC_membrane
SMART
PROSITE
PS50929
; ABC_TM1F
PRINTS