CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041161
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Polypyrimidine tract-binding protein 3 
Protein Synonyms/Alias
  
Gene Name
 Ptbp3 
Gene Synonyms/Alias
 Rod1 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
67SRVLHLRKIPCDVTEubiquitination[1]
139YSNHRELKTDNLPNQubiquitination[1]
425SGQRLYGKVLRATLSacetylation[2]
425SGQRLYGKVLRATLSubiquitination[1]
433VLRATLSKHQAVQLPubiquitination[1]
451QEDQGLTKDFSNSPLubiquitination[1]
505TEAGCSVKAFKFFQKubiquitination[1]
508GCSVKAFKFFQKDRKubiquitination[1]
512KAFKFFQKDRKMALIacetylation[2]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 554 AA 
Protein Sequence
MDGVVTDLIA VGLKRGSDEL LSSGVINGPS TMNSSTSAGV YANGNDNKKF KGDRPPCSPS 60
RVLHLRKIPC DVTEAEVISL GLPFGKVTNL LMLKGKSQAF LEMASEEAAV TMINYYTPVT 120
PHLRSQPVYI QYSNHRELKT DNLPNQARAQ AALQAVSAVQ SGNLSLPGAT ANEGTLLPGQ 180
SPVLRIIIEN LFYPVTLEVL HQIFSKFGTV LKIITFTKNN QFQALLQYAD PVNAQYAKMA 240
LDGQNIYNAC CTLRIDFSKL TSLNVKYNND KSRDFTRLDL PTGDGQPSLE PPMAAAFGAP 300
GIMSSPYAGA AGFAPAIAFP QAAGLSVPAV PGALGPLTLT SSAVSGRMAI PGASGMPGNS 360
VLLVTNLNPD FITPHGLFIL FGVYGDVHRV KIMFNKKENA LVQMADASQA QLAMNHLSGQ 420
RLYGKVLRAT LSKHQAVQLP REGQEDQGLT KDFSNSPLHR FKKPGSKNFQ NIFPPSATLH 480
LSNIPPSVTM DDLKNLFTEA GCSVKAFKFF QKDRKMALIQ LGSVEEAIQA LIELHNHDLG 540
ENHHLRVSFS KSTI 554 
Gene Ontology
 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0003723; F:RNA binding; IEA:InterPro.
 GO:0006397; P:mRNA processing; IEA:InterPro. 
Interpro
 IPR006536; HnRNP-L_PTB.
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR000504; RRM_dom. 
Pfam
  
SMART
 SM00360; RRM 
PROSITE
 PS50102; RRM 
PRINTS