CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017843
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Nucleoporin p58/p45 
Protein Synonyms/Alias
 Nucleoporin-like protein 1 
Gene Name
 Nupl1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
402HENVKVLKEQYLGYRacetylation[1]
410EQYLGYRKMFLGDAVubiquitination[2]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane (By similarity). 
Sequence Annotation
 REPEAT 7 8 1.
 REPEAT 30 31 2.
 REPEAT 44 45 3.
 REPEAT 63 64 4.
 REPEAT 68 69 5.
 REPEAT 476 477 6.
 REPEAT 480 481 7.
 REPEAT 501 502 8.
 REPEAT 507 508 9.
 REPEAT 517 518 10.
 REPEAT 519 520 11.
 REPEAT 533 534 12.
 REPEAT 556 557 13.
 REPEAT 566 567 14.
 REGION 7 567 14 X 2 AA repeats of F-G.
 MOD_RES 319 319 Phosphothreonine (By similarity).  
Keyword
 Alternative splicing; Coiled coil; Complete proteome; Glycoprotein; Membrane; mRNA transport; Nuclear pore complex; Nucleus; Phosphoprotein; Protein transport; Reference proteome; Repeat; Translocation; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 587 AA 
Protein Sequence
MATGFSFGSG TLGSTTVAPG GTGAGSGFSF GTVASSTPSV GLNFGSLGSS VTPASTSASA 60
GGFGTGLFGS KPATGFTLGG TSAGTAATTS ASTTGFSLGF SKPAASATPF ALPVTSTSAS 120
GLTLSSALTS TPAASTGFTL NNLGATPATT TTASTGLSLG GALAGLGGSL FQSGNTATSG 180
LGQNALSLSL GTTAPTSAAS NEGLGGIDFS TSSDKKSDKT GTRPEDSKAL KDENLPPVIC 240
QDVENLQKFV KEQKQVQEEI SRMSSKAMLK VQEDIKALKQ LLSLAASGLQ RNTLNIDKLK 300
LETAQELKNA EIALRTQKTP PGLQHENTAP ADYFRILVQQ FEVQLQQYRQ QIEELENHLA 360
TQASNSHITP QDLSMAMQKI YQTFVALAAQ LQSIHENVKV LKEQYLGYRK MFLGDAVDVF 420
EARRTEAKKW QNAPRVTTGP TPFSTMPNAA AVAMAATLTQ QQQPATGPQP SLGVSFGTPF 480
GSGIGTGLQS SGLGSSNLGG FGTSSGFGCG TTGASTFGFG TTDKPSGSLS AGFGSSSTSG 540
FNFSNPGITA SAGLTFGVSN PASAGFGTGG QLLQLKRPPA GNKRGKR 587 
Gene Ontology
 GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
 GO:0005643; C:nuclear pore; IEA:UniProtKB-SubCell.
 GO:0005487; F:nucleocytoplasmic transporter activity; IEA:Compara.
 GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW. 
Interpro
 IPR024882; Nucleoporin_p58/p45. 
Pfam
  
SMART
  
PROSITE
  
PRINTS