| Tag | Content |
|---|
| CPLM ID | CPLM-020461 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | pre-mRNA 3' end processing protein WDR33 |
Protein Synonyms/Alias | WD repeat-containing protein 33; WD repeat-containing protein WDC146 |
Gene Name | WDR33 |
Gene Synonyms/Alias | WDC146 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 65 | DYNPSVIKYLENRIW | ubiquitination | [1] | | 109 | PMNAVTTKFVRTSTN | ubiquitination | [1] |
|
Reference | [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW. Nature. 2013 Apr 18;496(7445):372-6. [ PMID: 23503661] |
Functional Description | Essential for both cleavage and polyadenylation of pre- mRNA 3' ends. |
Sequence Annotation | REPEAT 117 156 WD 1.
REPEAT 159 198 WD 2.
REPEAT 200 239 WD 3.
REPEAT 242 283 WD 4.
REPEAT 286 325 WD 5.
REPEAT 329 369 WD 6.
REPEAT 373 412 WD 7.
DOMAIN 618 770 Collagen-like.
MOD_RES 2 2 N-acetylalanine.
MOD_RES 7 7 Phosphoserine.
MOD_RES 46 46 N6-acetyllysine.
MOD_RES 1210 1210 Phosphoserine. |
Keyword | Acetylation; Alternative splicing; Collagen; Complete proteome; mRNA processing; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; WD repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1336 AA |
Protein Sequence | MATEIGSPPR FFHMPRFQHQ APRQLFYKRP DFAQQQAMQQ LTFDGKRMRK AVNRKTIDYN 60
PSVIKYLENR IWQRDQRDMR AIQPDAGYYN DLVPPIGMLN NPMNAVTTKF VRTSTNKVKC 120
PVFVVRWTPE GRRLVTGASS GEFTLWNGLT FNFETILQAH DSPVRAMTWS HNDMWMLTAD 180
HGGYVKYWQS NMNNVKMFQA HKEAIREARF IHNIPFSVVP IVMVKLFSKC ILGAEMHGLC 240
QFLGNFLHPI NTIFFFVFTH SPFCWHLSEV VLSRYQPLQY VRDVLSAAFC TGFLFSFMIN 300
NVYTLFLFII YCVRQEYFIP NKEFSL 326 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |