UniProt Accession

 C9J010_HUMAN; C9J010 

Genbank Protein ID

 AC098479; AC137936 

Genbank Nucleotide ID

  

Protein Name

 Monoacylglycerol lipase ABHD6 

Protein Synonyms/Alias

  

Gene Name

 ABHD6 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
126	LSIDGQVKRIHQFVE	ubiquitination	[1, 2, 3]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 173 AA 

Protein Sequence

Gene Ontology

 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0047372; F:acylglycerol lipase activity; IEA:Compara.
 GO:0060292; P:long term synaptic depression; IEA:Compara.
 GO:0030336; P:negative regulation of cell migration; IEA:Compara.
 GO:2000124; P:regulation of endocannabinoid signaling pathway; IEA:Compara. 

Interpro

 IPR000073; AB_hydrolase_1. 

Pfam

  

SMART

  

PROSITE

  

PRINTS

 PR00111; ABHYDROLASE.