CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040032
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Bardet-Biedl syndrome 4 protein 
Protein Synonyms/Alias
  
Gene Name
 BBS4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
104RSLFLLGKHKAAIEVubiquitination[1]
106LFLLGKHKAAIEVYNubiquitination[1, 2]
117EVYNEAAKLNQKDWEubiquitination[1, 2]
181KAIEVYKKAVEFSPEubiquitination[1]
282VAAISCLKRANYLAPubiquitination[1]
377LYNQGEKKNALAQYQubiquitination[1]
389QYQEMEKKVSLLKDNubiquitination[1]
394EKKVSLLKDNSSLEFubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 507 AA 
Protein Sequence
MIWNTRNSTY IFTAPEFPIL EKQNWLIHLH YIRKDYEACK AVIKEQLQET QGLCEYAIYV 60
QALIFRLEGN IQESLELFQT CAVLSPQSAD NLKQVARSLF LLGKHKAAIE VYNEAAKLNQ 120
KDWEISHNLG VCYIYLKQFN KAQDQLHNAL NLNRHDLTYI MLGKIHLLEG DLDKAIEVYK 180
KAVEFSPENT ELLTTLGLLY LQLGIYQKAF EHLGNALTYD PTNYKAILAA GSMMQTHGDF 240
DVALTKYRVV ACAVPESPPL WNNIGMCFFG KKKYVAAISC LKRANYLAPF DWKILYNLGL 300
VHLTMQQYAS AFHFLSAAIN FQPKMGELYM LLAVALTNLE DIENAKRAYA EAVHLDKCNP 360
LVNLNYAVLL YNQGEKKNAL AQYQEMEKKV SLLKDNSSLE FDSEMVEMAQ KLGAALQVGE 420
ALVWTKPVKD PKSKHQTTST SKPASFQQPL GSNQALGQAM SSAAAYRTLP SGAGGTSQFT 480
KPPSLPLEPE PAVESSPTET SEQIREK 507 
Gene Ontology
  
Interpro
 IPR013026; TPR-contain_dom.
 IPR011990; TPR-like_helical.
 IPR019734; TPR_repeat. 
Pfam
 PF13181; TPR_8 
SMART
 SM00028; TPR 
PROSITE
 PS50005; TPR
 PS50293; TPR_REGION 
PRINTS