CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029908
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Dynein, axonemal, heavy chain 9 
Protein Synonyms/Alias
 Protein Dnah9 
Gene Name
 Dnah9 
Gene Synonyms/Alias
 Dnahc9; RP23-215H18.2-001 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
273QLMTIKVKGMAELLDacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 4484 AA 
Protein Sequence
MPGAKEQAAL AESGDEEPGD PRLRLLGTFV ARSLRPAAGT WERCAGTAEA GRLLQAFLDH 60
NAASDPRPLL VVQSGPGGLV VTPGLDAGPE PSRARAKGLF FLRTKSEPPG NHSLRGTVLC 120
GDLPAVPLEH LAPLLSEVII PVLANEKNHL EWPHMVCQDI RHHAHTLKSD LLVIFEHMKG 180
RTLLPLPVGS EKLEFVDGHS EPVSDAIDKS TLYAVESAVI KWSHQVQVVL KRESSQALIQ 240
GQNPTPKVEL EFWKSRCEDL EHIYNQLMTI KVKGMAELLD KLQSSYLPAF KAMFRDVEAA 300
LTEAQDIHVH LLPLQQHLDI LENVEFPKVK GRLRPLLHVV CLIWATCKWY RSPGRLTVLL 360
QEICNLLIQQ ASNYLSPEDL LRSEVEESQK KLQVVSDTLS FFKQAFQDRR EHLHTYFKED 420
SEVRVWDFQA SLVFVRLDGF LGRVHMVEDL LKTALDLNNL EKLEFSGLRG NSLSQKVQRM 480
HEEFEEMYKV FLDCSYDCLD PKGTEFENDV CEFNKRVEDL DRRLGTILIQ AFDDAPDVEH 540
AFKLLDITGT LIKRPLVAQD VSQKYLALIR MFSTELDAVR VIYSQHIQKE AEHGFSPVHK 600
NMPTMAGGIC WAQELRQRVK GPFGNFKNIP HLYLQSAEGK RMIQKYEDLL SLLEEYERRL 660
YEDWCQTVSE KSQYNLSLPL LHRDPNTKQL SVNFNPQLIS VLKEMNYLQP SEVKTIPETA 720
AAMFSSREFY RQLVANLELM ANWYNKVIKI LLEVEFPLVE EELQNIDLRL RAAEETLSWK 780
TEGIWDYAMQ ITNSIHDLEQ RIQKTKDNVE EIQNIMKTWV SPIFKRKDGK KEWPLSLDDQ 840
QDHMEKYYSL IQESGLKIHA LVQENLVLFA ADPASSIWKS YVNYIDSMLL DGFFLAIECS 900
LKYLLENTEC KPGLTPVFEA QLNLVTPELV FHPSLDSGVK GGLYDIVQSL VTRIFAMPSL 960
VPRLSPHSGS PHYQGDLEDM ADLAGLRSVL MERVQNMMTL CCGYRNTLSQ YSYLYVEDRK 1020
EILGQFLLYG HVLTPEEIEA HAEDGIPENP PLLHHFKDQI DSYEKLYEEV VSLEPTKVFD 1080
GWMRVDVRPF KASLLNTIKK WSLMFKQHLV DFVTNSLSDL DSFIRSTESG LLKRVEKGDF 1140
QGLVEIMGHL VTLKERQSST DDMFEPLKQT IELLKSYEQE LPETVFKQLE ELPEKWKNMK 1200
KMAITVRQQV APLQANEVAL LRQRCSAFDD EQQQFQERFR KEAPFRFDSI NPHQMLDAWH 1260
VEIQHMESTM ATISKSADLF EVNVPDYKQL RQCRKEACQL KELWDTIGMV TSSIRAWEAT 1320
SWRNISVEAM DSECKQFARH IRNLDKEFRS WDAFTGLEST VLNTLTSLRA VAELQNPAIR 1380
DRHWRQLMQA TGVNFTMNQD TTLAHLLQLQ LHHFEDEVRG IVDRAVKEMS MEKTLKELQT 1440
TWASMEFQYE SHARTRVPLL QSDEDLIEVL EDNQVQLQNL MMSKYVAFFL EEVSSWQKKL 1500
STADSVISIW FEVQRTWSHL ESIFIGSEDI RAQLPQDSKR FEGIDSDFRE LAYDAQKTPN 1560
VVEATNKSGL YEKLEDIQSR LCLCEKALAE YLDTKRLSFP RFYFLSSSDL LDILSNGTAP 1620
QQVQRHLSKL FDNMAKMQFQ LDASQNPTKT SLGMYSKEEE YVAFSEACDC SGQVEIWLNR 1680
VLRHMKATVR HEMTEGVTAY EEKPRDQWLF DYPAQVALTC TQIWWTTEVG IAFARLEEGY 1740
ESAMKDYYKK QVAQLKTLIT MLIGPLSKGD RQKIMTICTI DVHARDVVAK MIAQKVDNAQ 1800
AFLWLSQLRH RWDDEAKHCF ANICDAQFLY SYEYLGNTPR LVITPLTDRC YITLTQSLHL 1860
TMSGAPAGPA GTGKTETTKD LGRALGIMVY VFNCSEQMDY KSCGNIYKGL AQTGAWGCFD 1920
EFNRISVEVL SVVAVQVKSI QDAIRDKKQR FSFLGEEISL DPSVGIFITM NPGYAGRTEL 1980
PENLKALFRP CAMVVPDFEL ISEIMLVAEG FIEARLLARK FITLYRLCKE LLSKQDHYDW 2040
GLRAIKSVLV VAGSLKRGDP DRPEDQVLMR SLRDFNIPKI VTDDMPVFMG LIGDLFPALD 2100
VPRKRDLDFE AVVRKAIVDL KLQAEDNFVL KVVQLEELLA VRHSVFVVGG AGTGKSQVLR 2160
SLHKTYQIMR RRPVWTDLNP KAVTNDELFG IINPATREWK DGLFSSIMRE LAIISHDGPK 2220
WILLDGDIDP MWIESLNTVM DDNKVLTLAS NERIPLNPTM RLLFEISHLR TATPATVSRA 2280
GILYINPADL GWNPPVSSWI DQREVQTERA NLTILFDKYL PTCLDTLRTR FKKIIPVPEQ 2340
SMIQMLCYLL ECLLTKEDIP ADCPKEIYEL YFVFAAIWAF GSAVIQDQLV DYRAEFSKWW 2400
LTEFKTVKFP SQGTVFDYYI DPETKKFEPW AKLIPQFEFD PEMPLQACLV HTSETIRVCY 2460
FMERLMQWRR PVMLVGPAGS GKSVLVGAKL SSLNPEEYMV KNVPFNYYTT SAMLQAVLEK 2520
PLEKKAGRNY GPPGNRKLIY FIDDMNMPEV DAYGTVQPHT VIRQHLDYGH WYDRNKLSLK 2580
EIMNVQYISC MNPTAGSFTI NPRLQRHFSV FALCFPGADA LSSIYSTILT HHLKFGNFPT 2640
TLQKSIPPLI NLAVTFHQKI ATTFLPTAIK FHYIFNLRDF ANIFQGILFS SVECVKSTQD 2700
LVKLYLHESS RVYRDKMVEE KDFNLFDKIQ TEFLKKNFDD SEEVLKQTQN LNMYCHFANG 2760
IGEPKYMPVQ SWDLLNQTLV EALESHNEVN AVMDLVLFED AIRHICHINR ILESPRGNAL 2820
LVGVGGSGKQ SLTKLAAFIS SMDVFQITLR KGYQIPDFKV DLASLCLKAG VKNLSTVFLM 2880
TDAHVADERF LVLINDLLAS GEIPDLYSDE EEENIINNVR NEVKSQGLMD SRENCWKFFI 2940
ERVQRQLKVT LCFSPVGNKL RIRSRKFPAI VNCTAINWFH EWPQEALESV SLRFLQNTKN 3000
IEPAVKQSIS KFMAFVHISV NKTSQSYLTN EQRYNYTTPK SFLEFIRLYQ SLLERNGKEL 3060
QAKVERLENG LLKLHSTSAQ VDDLKAKLAT QEVELRHKNE DTDKLIQVVG VETSKVSREK 3120
AIADEEEQKV ALIMLEVQQK QKDCEEDLAK AEPALTAAQA ALNTLNKTNL TELKSFGSPP 3180
LAVSNVSAAV MVLMAPGGKV PKDRSWKAAK ITMAKVDSFL DSLIHFDKEN IHENCLKAIR 3240
PYLQDPAFNP EFVATKSYAA AGLCSWVINI VRFYEVFCDV EPKRQALNKA TSDLTTAQEK 3300
LAAIKAKITH LNENLAKLTT KFEKATAEKL KCQQEAELTA GTISLANRLV GGLASENIRW 3360
AEAVQNFRQQ ERTLCGDILL TTAFISYLGF FTKKYRKSLM DGTWRPYLSQ LKVPIPTTPT 3420
LDPLRMLTDD AEVAAWQNEG LPADRMSMEN ATILINCERW PLMVDPQLQG IKWIKNKYGE 3480
ELRVTQIGQK GCLQTIERAL EAGDVVLIEN LEESIDPVLG PLLGREVIKK GRFIKIGDKE 3540
CEFNPKFRLI LHTKLANPHY QPELQAQATL INFTVTRDGL EDQLLAAVVS MERPDLEQLK 3600
SDLTKQQNGF KITLKTLEDN LLSRLSSASG NFLGETALVE NLEVTKQTAA DVEEKVQEAK 3660
LTEVKINEAR EHYRPAAARA SLLYFIMNDL SKIHPMYQFS LKAFSIVFQK AVEKAAPSES 3720
VTERVTNLID SITFSVYQYT TRGLFECDKL TYLAQLTFQI LLVNQEVNAA ELDFLLRAPV 3780
QTGTPSPMEF LSHQAWGGIK ALSSMEEFCN LDRDIEGSAK SWKKFVESEC PEKEKFPQEW 3840
KNKTALQRLC MMRAMRPDRM TYAMRDFVEE KLGSKYVMGR ALDFVTSFEE SGPATPMFFI 3900
LSPGVDPLKD VENQGKKLGY TFNNRNFHNV SLGQGQEVVA EAALDLAAKK GHWVILQNIH 3960
LVAKWLSTLE KKLEELSEES HPDFRVFISA EPAPSPEGHI IPQGILENSI KITNEPPTGM 4020
HANLHKALDN FTQDTLEMCS RETEFKTILF ALCYFHAVVA ERRKFGPQGW NRSYPFNTGD 4080
LTISVNVLYN FLEANTKVPY DDLRYLFGEI MYGGHITDDW DRRLCRTYLE EFIRPEMLEG 4140
ELSLAPGFPL PGNMDYSGYH QYIDAELPPE SPYLYGLHPN AEIGFLTQTS EKLFRTVLEM 4200
QPRDSQAGDG AGITREEKVK TFLEEILDRM TDEFNIAELM AKVEERTPYI VVALQECERM 4260
NILTREIQRS LRELHLGLQG ELTMTSEMEN LQNALYLDVV PESWARRAYP STAGLAAWFL 4320
DLLNRIKELE SWTGDFLMPS TVWLTGFFNP QSFLTAIMQS MARKNEWPLD QMALQCDVTK 4380
KNREEFRSPP REGAYIYGLF MEGACWDTQT GIIAEAKLKD LTPPMPVMFL KAIPADKQDC 4440
RSVYACPVYK TCQRGPTYVW TFNLKTKENP SKWVLAGVAL LLQI 4484 
Gene Ontology
 GO:0035085; C:cilium axoneme; IEA:Compara.
 GO:0030286; C:dynein complex; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0016887; F:ATPase activity; IEA:InterPro.
 GO:0003777; F:microtubule motor activity; IEA:InterPro.
 GO:0006200; P:ATP catabolic process; IEA:GOC.
 GO:0007018; P:microtubule-based movement; IEA:InterPro. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR011704; ATPase_dyneun-rel_AAA.
 IPR026983; DHC_fam.
 IPR024743; Dynein_HC_stalk.
 IPR024317; Dynein_heavy_chain_D4_dom.
 IPR004273; Dynein_heavy_dom.
 IPR013594; Dynein_heavy_dom-1.
 IPR013602; Dynein_heavy_dom-2.
 IPR027417; P-loop_NTPase. 
Pfam
 PF07728; AAA_5
 PF12780; AAA_8
 PF08385; DHC_N1
 PF08393; DHC_N2
 PF03028; Dynein_heavy
 PF12777; MT 
SMART
 SM00382; AAA 
PROSITE
  
PRINTS