UniProt Accession

 BFR1_YEAST; P38934; D6W2Q7 

Genbank Protein ID

 U06870; Z75106; BK006948 

Genbank Nucleotide ID

 AAA19589.1; CAA99411.1; DAA10973.1 

Protein Name

 Nuclear segregation protein BFR1 

Protein Synonyms/Alias

 Brefeldin A resistance protein 1 

Gene Name

 BFR1 

Gene Synonyms/Alias

 YOR198C 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
83	SNIHDSIKQLDAQIK	acetylation	[1]
113	FSSTAEAKQRINEIE	ubiquitination	[2, 3]
148	QSLNKLIKDLVNIEP	acetylation	[1]
171	KAKINQLKEELNGLN	acetylation	[1]
192	QFEENQQKLNDIHSK	acetylation	[1]
276	DMGKLQEKLTHAKIP	ubiquitination	[3]
373	QPASIFNKVDGKFTL	ubiquitination	[3]
410	KITVEQLKKKHEELL	acetylation	[1]
419	KHEELLSKQEEQTKQ	acetylation	[1]
425	SKQEEQTKQNIESVE	ubiquitination	[3]
445	LNLDYSNKEQQVKKE	ubiquitination	[3]

Reference

 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919]
 [2] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047]
 [3] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 

Functional Description

 Implicated in secretion, nuclear segregation and in maintenance of cell size. 

Sequence Annotation

 MOD_RES 260 260 Phosphoserine.
 MOD_RES 336 336 Phosphothreonine.
 MOD_RES 369 369 Phosphoserine.  

Keyword

 Coiled coil; Complete proteome; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 470 AA 

Protein Sequence

Gene Ontology

 GO:0042175; C:nuclear outer membrane-endoplasmic reticulum membrane network; IDA:SGD.
 GO:0005844; C:polysome; IDA:SGD.
 GO:0003723; F:RNA binding; IDA:SGD.
 GO:0007126; P:meiosis; IMP:SGD.
 GO:0016071; P:mRNA metabolic process; IPI:SGD.
 GO:0007088; P:regulation of mitosis; IMP:SGD. 

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PRINTS