Tag | Content |
---|
CPLM ID | CPLM-005655 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc finger protein 2 |
Protein Synonyms/Alias | Zinc finger homeodomain protein 2 |
Gene Name | zfh2 |
Gene Synonyms/Alias | zfh-2; CG1449 |
Created Date | July 27, 2013 |
Organism | Drosophila melanogaster (Fruit fly) |
NCBI Taxa ID | 7227 |
Lysine Modification | Position | Peptide | Type | References |
---|
1299 | SDGPVGIKQERLEQE | acetylation | [1] | 1839 | QKANLPMKVVKHWFR | acetylation | [1] | 2117 | KKMQIVGKTFEKNVA | acetylation | [1] |
|
Reference | [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation. Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C. Sci Signal. 2011 Jul 26;4(183):ra48. [ PMID: 21791702] |
Functional Description | Involved in the development of the embryonic central nervous system. |
Sequence Annotation | ZN_FING 133 156 C2H2-type 1. ZN_FING 559 582 C2H2-type 2. ZN_FING 614 638 C2H2-type 3. ZN_FING 732 756 C2H2-type 4. ZN_FING 897 916 C2H2-type 5; degenerate. ZN_FING 940 964 C2H2-type 6. ZN_FING 999 1023 C2H2-type 7. ZN_FING 1074 1098 C2H2-type 8. ZN_FING 1210 1233 C2H2-type 9. ZN_FING 1341 1365 C2H2-type 10. ZN_FING 1438 1462 C2H2-type 11. ZN_FING 1477 1500 C2H2-type 12; degenerate. ZN_FING 1513 1535 C2H2-type 13. ZN_FING 1541 1564 C2H2-type 14. DNA_BIND 1797 1856 Homeobox 1. DNA_BIND 2154 2213 Homeobox 2. ZN_FING 2234 2256 C2H2-type 15. ZN_FING 2371 2393 C2H2-type 16. DNA_BIND 2760 2819 Homeobox 3. MOD_RES 1337 1337 Phosphothreonine. MOD_RES 2361 2361 Phosphoserine. MOD_RES 2450 2450 Phosphoserine. MOD_RES 2451 2451 Phosphoserine. MOD_RES 2749 2749 Phosphoserine. MOD_RES 2751 2751 Phosphoserine. |
Keyword | Complete proteome; DNA-binding; Homeobox; Metal-binding; Nucleus; Phosphoprotein; Reference proteome; Repeat; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 3005 AA |
Protein Sequence | MSSFDVETFN GKIVYNLDGS AHIIATDNTN GGGSGSGQNC YGSTTNSLKN LSKDKGRGQE 60 EKDIEHPSQY HREQSDNKRQ EEAVDNRPGV ESLGSACYKS SPKIHSFRVV SAQDANSTCQ 120 DQIRAFKIQK PILMCFICKL SFGNVKSFSL HANTEHRLNL EELDQQLLNR EYSSAIIQRN 180 MDEKPQISFL QPLANNDASA DTNDTEKLQT ATEGSDATLP SSPQPVFRNV SELEPENKQE 240 TEQNRLLNQD REQEPESDQH TSSSKMAAPS AYIPLSSPKV AGKLTVKFGS LNSATAKTNN 300 LSKVSSTSSP PSTYASGEVL SPSTDNISNH KSTHCNQETE PPSSSSSEVE MKIGSMSTSP 360 QTNDSDVPCS GFLQMQHMTT GGAYTPQVSS FHASLAALAA NESNDNRVKL ITEFLQQQLQ 420 QHQSSLFPSP CPDHPDLNGV DCKTCELLDI QQRSKSPSSS HHQFSQSLPQ LQIQSQPQQT 480 PHRSPCSNSV ALPVSPSASS VASVGNASTA TSSFTIGACS EHINGRPQGV DCARCEMLLN 540 SARLNSGVQM STRNSCKTLK CPQCNWHYKY QETLEIHMRE KHPDGESACG YCLAGQQHPR 600 LARGESYSCG YKPYRCEICN YSTTTKGNLS IHMQSDKHLN NMQELNSSQN MVAAAAAAAV 660 TGKLLLSSSS PQVTAACPSN SGSGAGSGSS NIVGGTASLS GNATPSVTGA NSSNANAGSN 720 TNNAGTKPKP SFRCDICSYD TSVARNLRIH MTSEKHTHNM AVLQNNIKHI QAFNFLQQQQ 780 QSGTGNIASH SSGSFMPEVA LADLAYNQAL MIQLLHQQQQ HQQSANTKLS PSSSPVSTPD 840 QFSFSPKPIK LNHGTGAAMG IGMAMGMGMS HSNEVSCELS GDPHPLTKTD KWPMAFYSCL 900 VCDCYSTNNL DDLNQHLLLD RSRQSSSASS EIMVIHNNNY ICRLCNYKTN LKANFQLHSK 960 TDKHLQKLNF INHIREGGPQ NEYKMQYQQQ QLAANVVQLK CNCCDFHTNS IQKLSLHTQQ 1020 MRHDTMRMIF QHLLYIVQQS EMHNKSSGSA EDDPQCACPD EDQQLQLQSS KKLLLCQLCN 1080 FTAQNIHEMV QHVKGIRHLQ VEQFICLQRR SENQEIPALN EVFKVTEWVM ENEDVSLAPG 1140 LNLARTTTND ATTDASYAAA SSAAVPAIPD VSMFSPTSPS SCATSCDKNL SQIVLPNVNN 1200 LGSGVPTTVF KCNLCEYFVQ SKSEIAAHIE TEHSCAESDE FITIPTNTAA LQAFQTAVAA 1260 AALAAVHQRC AVINPPTQDT VDEDKDLDTN VSDGPVGIKQ ERLEQEVDRT TSMDVTKDLA 1320 SQATDFGAPE SPKVAETEVG VQCPLCLENH FREKQYLEDH LTSVHSVTRD GLSRLLLLVD 1380 QKALKKESTD IACPTDKAPY ANTNALERAP TPIENTCNVS LIKSTSANPS QSVSLQGLSC 1440 QQCEASFKHE EQLLKHAQQN QHFSLQNGEY LCLAASHISR PCFMTFRTIP TMISHFQDLH 1500 MSLIISERHV YKYRCKQCSL AFKTQEKLTT HMLYHSMRDA TKCSFCQRNF RSTQALQKHM 1560 EQAHAEDGTP STRTNSPQTP MLSTEETHKH LLAESHAVER EVSGSDVSPI ELETHLNKET 1620 RHLSPTPMSL DSQSHQKHLA TFAALLKQQQ CNSDAGGLHP EALSMSTGEM PPQLQGLQNL 1680 QHIQQHFGAV AAAAGLPINP VDMLNIMQFH HLMSLNFMNL APPLVFGANA AGNAVSGPSA 1740 LNNSITTSTA TSASGLGDTH LTSGVSSIPV DSGKATAVPP QTQLNANANS QQLASNQKRA 1800 RTRITDDQLK ILRAHFDINN SPSEESIMEM SQKANLPMKV VKHWFRNTLF KERQRNKDSP 1860 YNFNNPPSTT LNLEEYERTG QAKVTPLNDT CSVAVTGPMT SSTISLPPSG NINLSSKENA 1920 TSKVLAAGKA NASGPVTFSA TVPVSTPLSR PESTNSSGNI SDYIGNNIFF GQLGSKEQIL 1980 PYSLDGQIKS EPQDDMIGAT DFAYQTKQHS SFSFLKQQQD LVDPPEQCLT NQNADTAQDQ 2040 SLLAGSSLAS NCQSQQQINI FETKSESGSS DVLSRPPSPN SGAAGNVYGS MNDLLNQQLE 2100 NMGSNMGPPK KMQIVGKTFE KNVAPMVTSG SVSTQFESNS SNSSSSSSST SGGKRANRTR 2160 FTDYQIKVLQ EFFENNSYPK DSDLEYLSKL LLLSPRVIVV WFQNARQKQR KIYENQPNNT 2220 LFENEETKKQ NINYACKKCN LVFQRYYELI RHQKNHCFKE ENNKKSAKAQ IAAAQIAQNL 2280 SSEDSNSSMD IHHVGICPPG SAVASHTLST PGSAAPLPGQ YTQHSFGALP SPQHLFAKSS 2340 SLTDFSPSTT PTPPQRERSN SLDQIQRPPK FDCDKCELNF NQLEKLREHQ LLHLMNPGNI 2400 CSDVGQNSNP EANFGPFGSI LQSLQQAAAQ QQQQHHQQPP TKKRKYSDCS SNADEMQSLS 2460 ELEASQKKHE YLYKYFMQNE TSQEVKQQFL MQQQQKKLEQ GNECDFELDF LTNFYQQNEL 2520 KKVSNYDFLL QYYRTHEEAK SSQQHTFSSS KKPTIEFLLQ YYQLNESKKF FQLVASPQII 2580 PDVPGYKPSL RIPKSTSDEA PYIGETSLEQ ATELQREKQD EQLRIDRPSE ENDLSMNKNK 2640 VENINNNNIN VDQSNLTETN GGVPSVETKE ECTQESSLIA MDDENKYLCT RSKQKDDKEK 2700 SHYLHNLEDF LDATMIENNS QTLTFNDDEK ACQKDELTQN SNAIEKRSSV SPVNVSSKQN 2760 KRLRTTILPE QLNFLYECYQ SESNPSRKML EEISKKVNLK KRVVQVWFQN SRAKDKKSRN 2820 QRHYAHISDD NSYDGSSGKE VYSDLRSNGI TVDTDLETNL QDCQLCQVTQ VNIRKHAFSV 2880 EHISKMKKLL EQTTELYAQS NGSGSEDNDS DREKRFYNLS KAFLLQHVVT NATSHAIHTA 2940 RQDSDVIAEG NCILNYDTNG GDSKSHVQHN LPNEVVSEDA RKIAGNQELM QQLFNRNHIT 3000 VIGGK 3005 |
Gene Ontology | GO:0005634; C:nucleus; IDA:FlyBase. GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IDA:FlyBase. GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase. GO:0007399; P:nervous system development; IEP:FlyBase. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |