CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038228
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 LIM domain-binding protein 3 
Protein Synonyms/Alias
  
Gene Name
 Ldb3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
21GFRLQGGKDFNMPLTubiquitination[1]
84SLTLQKSKRPIPISTubiquitination[1]
128RFNPSVLKDSALSTHubiquitination[1]
136DSALSTHKPIEVKGLacetylation[2]
136DSALSTHKPIEVKGLubiquitination[1]
141THKPIEVKGLGGKATubiquitination[1]
204PVYQAVIKTQSKPEDubiquitination[1]
208AVIKTQSKPEDEADEacetylation[2]
463KSTTTVSKQTLPRGAubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] The fasted/fed mouse metabolic acetylome: N6-acetylation differences suggest acetylation coordinates organ-specific fuel switching.
 Yang L, Vaitheesvaran B, Hartil K, Robinson AJ, Hoopmann MR, Eng JK, Kurland IJ, Bruce JE.
 J Proteome Res. 2011 Sep 2;10(9):4134-49. [PMID: 21728379] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; LIM domain; Metal-binding; Reference proteome; Zinc. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 679 AA 
Protein Sequence
MSYSVTLTGP GPWGFRLQGG KDFNMPLTIS RITPGSKAAQ SQLSQGDLVV AIDGVNTDTM 60
THLEAQNKIK SASYNLSLTL QKSKRPIPIS TTAPPIQSPL PVIPHQKVVA NSPANADYQE 120
RFNPSVLKDS ALSTHKPIEV KGLGGKATII HAQYNTPISM YSQDAIMDAI AGQAQAQGSD 180
FSGSLPVKDL AVDSASPVYQ AVIKTQSKPE DEADEWARRS SNLQSRSFRI LAQMTGTEYM 240
QDPDEEALRR SSTPIEHAPV CTSQATSPLL PASAQSPAAA SPIAASPTLA TAAATHAAAA 300
SAAGPAASPV ENPRPQASAY SPAAAASPAP SAHTSYSEGP AAPAPKPRVV TTASIRPSVY 360
QPVPASSYSP SPGANYSPTP YTPSPAPAYT PSPAPTYTPS PAPTYSPSPA PAYTPSPAPN 420
YTPTPSAAYS GGPSESASRP PWVTDDSFSQ KFAPGKSTTT VSKQTLPRGA PAYNPTGPQV 480
TPLARGTFQR AERFPASSRT PLCGHCNNVI RGPFLVAMGR SWHPEEFNCA YCKTSLADVC 540
FVEEQNNVYC ERCYEQFFAP ICAKCNTKIM GEVMHALRQT WHTTCFVCAA CKKPFGNSLF 600
HMEDGEPYCE KDYINLFSTK CHGCDFPVEA GDKFIEALGH TWHDTCFICA VCHVNLEGQP 660
FYSKKDKPLC KKHAHAINV 679 
Gene Ontology
 GO:0030018; C:Z disc; IDA:MGI.
 GO:0051371; F:muscle alpha-actinin binding; IDA:MGI.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0045214; P:sarcomere organization; IMP:MGI. 
Interpro
 IPR001478; PDZ.
 IPR006643; ZASP.
 IPR001781; Znf_LIM. 
Pfam
 PF00412; LIM
 PF00595; PDZ 
SMART
 SM00132; LIM
 SM00228; PDZ
 SM00735; ZM 
PROSITE
 PS00478; LIM_DOMAIN_1
 PS50023; LIM_DOMAIN_2
 PS50106; PDZ 
PRINTS