CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024266
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Carbonic anhydrase 
Protein Synonyms/Alias
 Carbonate dehydratase 
Gene Name
 cynT 
Gene Synonyms/Alias
 MSMEG_6082; MSMEI_5922 
Created Date
 July 27, 2013 
Organism
 Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) 
NCBI Taxa ID
 246196 
Lysine Modification
Position
Peptide
Type
References
11SNPVAAWKALKDGNApupylation[1]
Reference
 [1] Expansion of the mycobacterial "PUPylome".
 Watrous J, Burns K, Liu WT, Patel A, Hook V, Bafna V, Barry CE 3rd, Bark S, Dorrestein PC.
 Mol Biosyst. 2010 Feb;6(2):376-85. [PMID: 20094657
Functional Description
 Catalyzes the reversible hydration of carbon dioxide to form bicarbonate (By similarity). 
Sequence Annotation
 METAL 51 51 Zinc (By similarity).
 METAL 53 53 Zinc (By similarity).
 METAL 104 104 Zinc (By similarity).
 METAL 107 107 Zinc (By similarity).
 CROSSLNK 11 11 Isoglutamyl lysine isopeptide (Lys-Gln)  
Keyword
 Complete proteome; Isopeptide bond; Lyase; Metal-binding; Reference proteome; Ubl conjugation; Zinc. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 206 AA 
Protein Sequence
MPNSNPVAAW KALKDGNARF VAGQPLHPSQ GIERRASLTQ AQRPTAVVFG CGDSRVAAEI 60
LFDQGLGDMF VVRTAGHVID NAVLGSIEYA VTVLKVPLIV VLGHDSCGAV KATLSALDEG 120
EVPSGFVRDI VERVTPSILL GRKAGLSRVD EFEAQHVNET VAQLQMRSTA IAQGLAAGTQ 180
AIVGTTYHLA DGRVELRSHL GDIGEV 206 
Gene Ontology
 GO:0004089; F:carbonate dehydratase activity; IEA:EC.
 GO:0008270; F:zinc ion binding; ISS:UniProtKB.
 GO:0015976; P:carbon utilization; IEA:InterPro. 
Interpro
 IPR001765; Carbonic_anhydrase.
 IPR015892; Carbonic_anhydrase_CS. 
Pfam
 PF00484; Pro_CA 
SMART
 SM00947; Pro_CA 
PROSITE
 PS00704; PROK_CO2_ANHYDRASE_1
 PS00705; PROK_CO2_ANHYDRASE_2 
PRINTS