CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-045474
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Uncharacterized protein 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
60FSETGAGKHVPRAVFacetylation[1]
60FSETGAGKHVPRAVFubiquitination[2]
96PEQLITGKEDAANNYacetylation[1]
96PEQLITGKEDAANNYubiquitination[2]
214YRGDVVPKDVNAAIAacetylation[1]
214YRGDVVPKDVNAAIAubiquitination[2]
224NAAIATIKTKQKKKKacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; GTP-binding; Microtubule; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 346 AA 
Protein Sequence
MRECISIHVG QAGVQIGNTC WVLYCLEHGI QPDGQMPSDK TIGGGDDSFN TFFSETGAGK 60
HVPRAVFVDL EPTVIDEVRT GTYRQLFHPE QLITGKEDAA NNYARGHYTI AYTNLNRLIG 120
QIVSSITASL RFDGALNVDL TEFQTNLVPY PRIHFPLATY ASVISAEKAY HEQLSVAEIT 180
NACFEPANQM VKCDPRHGKY MACCLLYRGD VVPKDVNAAI ATIKTKQKKK KTKRTIQFVD 240
WCPTGFKVGI NYQPPTVVHG GDLAKVQRAV CMLRNTTAIA EAWARLDHKF DPMYAKRAFV 300
HWYVGEGMEE GEFSEAREDT AALEKDYEEV GMDSVEGEGE EEGEEY 346 
Gene Ontology
 GO:0005874; C:microtubule; IEA:UniProtKB-KW.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0003924; F:GTPase activity; IEA:InterPro.
 GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro.
 GO:0007017; P:microtubule-based process; IEA:InterPro.
 GO:0051258; P:protein polymerization; IEA:InterPro. 
Interpro
 IPR002452; Alpha_tubulin.
 IPR008280; Tub_FtsZ_C.
 IPR000217; Tubulin.
 IPR018316; Tubulin/FtsZ_2-layer-sand-dom.
 IPR023123; Tubulin_C.
 IPR003008; Tubulin_FtsZ_GTPase. 
Pfam
 PF00091; Tubulin
 PF03953; Tubulin_C 
SMART
 SM00865; Tubulin_C 
PROSITE
  
PRINTS
 PR01162; ALPHATUBULIN.
 PR01161; TUBULIN.