CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-003143
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Spermidine N(1)-acetyltransferase 
Protein Synonyms/Alias
 Diamine acetyltransferase; SAT 
Gene Name
 speG 
Gene Synonyms/Alias
 b1584; JW1576 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
68VVECDGEKAGLVELVacetylation[1]
97ISPEYQGKGLATRAAacetylation[1]
105GLATRAAKLAMDYGFacetylation[1]
126KLYLIVDKENEKAIHacetylation[1]
130IVDKENEKAIHIYRKacetylation[1]
174HQYLAEHKTPGQTLLacetylation[1]
182TPGQTLLKPTAQ***acetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618
Functional Description
 Regulates polyamine concentration by their degradation. Acts on spermidine, forming N(1)- and N(8)-acetylspermidine. 
Sequence Annotation
 DOMAIN 7 167 N-acetyltransferase.  
Keyword
 Acyltransferase; Complete proteome; Cytoplasm; Direct protein sequencing; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 186 AA 
Protein Sequence
MPSAHSVKLR PLEREDLRYV HQLDNNASVM RYWFEEPYEA FVELSDLYDK HIHDQSERRF 60
VVECDGEKAG LVELVEINHV HRRAEFQIII SPEYQGKGLA TRAAKLAMDY GFTVLNLYKL 120
YLIVDKENEK AIHIYRKLGF SVEGELMHEF FINGQYRNAI RMCIFQHQYL AEHKTPGQTL 180
LKPTAQ 186 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0004145; F:diamine N-acetyltransferase activity; IEA:EC. 
Interpro
 IPR016181; Acyl_CoA_acyltransferase.
 IPR000182; GNAT_dom. 
Pfam
 PF00583; Acetyltransf_1 
SMART
  
PROSITE
 PS51186; GNAT 
PRINTS