CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024992
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Matrix metallopeptidase 19 
Protein Synonyms/Alias
 Matrix metallopeptidase 19, isoform CRA_a 
Gene Name
 Mmp19 
Gene Synonyms/Alias
 mCG_18673 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
258GIQALYGKRSPETRDubiquitination[1]
372MSPGFPMKFNRVEPNubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
 ACT_SITE 214 214 By similarity.  
Keyword
 Calcium; Disulfide bond; Hydrolase; Metal-binding; Metalloprotease; Protease; Repeat; Zinc. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 527 AA 
Protein Sequence
MDWQQLWLAF LLPMTVSGRA LGPTEKEAVL DYLLQYGYLQ KPLEGADDFR LEDITEALRT 60
FQEASGLPIS GQMDDATRAR MKQPRCGLED PFNQKSLKYL LLGHWRKKNL TFRIFNVPST 120
LSLPRVRAAL HQAFKYWSSV APLTFREVKA GWADIRLSFH GRQSLYCSNT FDGPGKVLAH 180
ADIPELGSIH FDKDELWTEG TYQGVNLRII AAHEVGHALG LGHSRYTQAL MAPVYAGYQP 240
FFKLHPDDVA GIQALYGKRS PETRDEEEET EMLTVSPVTA KPGPMPNPCS GEVDAMVLGP 300
RGKTYAFKGD YVWTVTDSGP GPLFQISALW EGLPGNLDAA VYSPRTRRTH FFKGNKVWRY 360
VDFKMSPGFP MKFNRVEPNL DAALYWPVNQ KVFLFKGSGY WQWDELARTD LSRYPKPIKE 420
LFTGVPDRPS AAMSWQDGQV YFFKGKEYWR LNQQLRVAKG YPRNTTHWMH CGSQTPDTNS 480
STGDVTPSTT DTVLGTTPST MGSTLDIPSA TDSASLSFSA NVTLLGA 527 
Gene Ontology
 GO:0031012; C:extracellular matrix; IEA:InterPro.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0004222; F:metalloendopeptidase activity; ISS:MGI.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0001554; P:luteolysis; IEA:Compara.
 GO:0001541; P:ovarian follicle development; IEA:Compara.
 GO:0001542; P:ovulation from ovarian follicle; IEA:Compara.
 GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
 GO:0051591; P:response to cAMP; IEA:Compara.
 GO:0009725; P:response to hormone stimulus; IEA:Compara. 
Interpro
 IPR000585; Hemopexin-like_dom.
 IPR018487; Hemopexin-like_repeat.
 IPR018486; Hemopexin_CS.
 IPR024079; MetalloPept_cat_dom.
 IPR001818; Pept_M10_metallopeptidase.
 IPR021190; Pept_M10A.
 IPR016293; Pept_M10A_Metazoans.
 IPR006026; Peptidase_Metallo.
 IPR002477; Peptidoglycan-bd-like. 
Pfam
 PF00045; Hemopexin
 PF00413; Peptidase_M10
 PF01471; PG_binding_1 
SMART
 SM00120; HX
 SM00235; ZnMc 
PROSITE
 PS00024; HEMOPEXIN 
PRINTS
 PR00138; MATRIXIN.