CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031174
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 28S ribosomal protein S27, mitochondrial 
Protein Synonyms/Alias
 cDNA FLJ54536, highly similar to Mitochondrial 28S ribosomal protein S27 
Gene Name
 MRPS27 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
59DLASLMDKTFERKLPubiquitination[1]
279RALQVMEKVAASPEDubiquitination[2]
340IEETEQSKLPQYLERubiquitination[2]
354RFKALHSKLQALGKIubiquitination[2]
375SLTTQLVKEKLSTCEubiquitination[2, 3]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Ribonucleoprotein; Ribosomal protein. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 428 AA 
Protein Sequence
MAASIVRRGM LLARQVVLPQ LSPAGKRYLL SSAYVDSHKW EAREKEHYCL ADLASLMDKT 60
FERKLPVSSL TISRLIDNIS SREEIDHAEY YLYKKGECSS SNPQNYSRFR HSPNCWYLRN 120
WTIHTWIRQC LKYDAQDKAL YTLVNKVQYG IFPDNFTFNL LMDSFIKKEN YKDALSVVFE 180
VMMQEAFEVP STQLLSLYVL FHCLAKKTDF SWEEERNFGA SLLLPGLKQK NSVGFSSQLY 240
GYALLGKVEL QQGLRAVYHN MPLIWKPGYL DRALQVMEKV AASPEDIKLC REALDVLGAV 300
LKALTSADGA SEEQSQNDED NQGSEKLVEQ LDIEETEQSK LPQYLERFKA LHSKLQALGK 360
IESEGLLSLT TQLVKEKLST CEAEDIATYE QNLQQWHLDL VQLIQREQQQ REQAKQEYQA 420
QKAAKASA 428 
Gene Ontology
 GO:0005840; C:ribosome; IEA:UniProtKB-KW. 
Interpro
 IPR002885; Pentatricopeptide_repeat.
 IPR019266; Ribosomal_S27_mit. 
Pfam
 PF10037; MRP-S27 
SMART
  
PROSITE
 PS51375; PPR 
PRINTS