CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007380
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ubiquitin-like-specific protease 2 
Protein Synonyms/Alias
  
Gene Name
 ULP2 
Gene Synonyms/Alias
 SMT4; YIL031W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
682KNLRHTLKLLQLNYIacetylation[1]
Reference
 [1] Preparative peptide isoelectric focusing as a tool for improving the identification of lysine-acetylated peptides from complex mixtures.
 Xie H, Bandhakavi S, Roe MR, Griffin TJ.
 J Proteome Res. 2007 May;6(5):2019-26. [PMID: 17397211
Functional Description
 Insertion mutation in SMT4 confers temperature and benomyl sensitivity; high copy suppressor of a temperature sensitive mutation in MIF2. 
Sequence Annotation
 MOD_RES 788 788 Phosphoserine.
 MOD_RES 903 903 Phosphoserine.
 MOD_RES 983 983 Phosphoserine.
 MOD_RES 984 984 Phosphoserine.  
Keyword
 Complete proteome; Hydrolase; Phosphoprotein; Protease; Reference proteome; Thiol protease. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1034 AA 
Protein Sequence
MSARKRKFNS LKPLDTLNSS RASSPRSSAS LPPKRYNTFR KDPKIVDHLN NASTKDFLPV 60
LSMNSESKRQ IELSDNDVDN NDEGEGVNSG CSDQDFEPLQ SSPLKRHSSL KSTSNGLLFQ 120
MSNNLGNGSP EPAVASTSPN GSIISTKLNL NGQFSCVDSK TLRIYRHKAP CIMTFVSDHN 180
HPKFSLYFQQ SVIYNSQVNL LDDVELIILD KKNSFMAIIL KDLKKVKMIL DVNNSSININ 240
TNILIWSTAS SASNKKIKSI KRFLLMSYSS SIKVEILDHK EQILERLKHL IHPISSSSPS 300
LNMERAINST KNAFDSLRLK KTKLSTNDDE SPQIHTHFLS NKPHGLQSLT KRTRIASLGK 360
KEHSISVPKS NISPSDFYNT NGTETLQSHA VSQLRRSNRF KDVSDPANSN SNSEFDDATT 420
EFETPELFKP SLCYKFNDGS SYTITNQDFK CLFNKDWVND SILDFFTKFY IESSIEKSII 480
KREQVHLMSS FFYTKLISNP ADYYSNVKKW VNNTDLFSKK YVVIPINISY HWFSCIITNL 540
DAILDFHQNK DKNDAINSDE ISINNPLVNI LTFDSLRQTH SREIDPIKEF LISYALDKYS 600
IQLDKTQIKM KTCPVPQQPN MSDCGVHVIL NIRKFFENPV ETIDVWKNSK IKSKHFTAKM 660
INKYFDKNER NSARKNLRHT LKLLQLNYIS YLKKENLYEE VMQMEEKKST NINNNENYDD 720
DDEEIQIIEN IDQSSKDNNA QLTSEPPCSR SSSISTTERE PTELHNSVVR QPTGEIITDN 780
EDPVRAASPE TASVSPPIRH NILKSSSPFI SESANETEQE EFTSPYFGRP SLKTRAKQFE 840
GVSSPIKNDQ ALSSTHDIMM PSPKPKRIYP SKKIPQLSSH VQSLSTDSME RQSSPNNTNI 900
VISDTEQDSR LGVNSESKNT SGIVNRDDSD VNLIGSSLPN VAEKNHDNTQ ESNGNNDSLG 960
KILQNVDKEL NEKLVDIDDV AFSSPTRGIP RTSATSKGSN AQLLSNYGDE NNQSQDSVWD 1020
EGRDNPILLE DEDP 1034 
Gene Ontology
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0016929; F:SUMO-specific protease activity; IDA:SGD.
 GO:0030261; P:chromosome condensation; IMP:SGD.
 GO:0007094; P:mitotic spindle assembly checkpoint; IGI:SGD.
 GO:0006276; P:plasmid maintenance; IMP:SGD.
 GO:0016926; P:protein desumoylation; IMP:SGD.
 GO:0006508; P:proteolysis; IEA:UniProtKB-KW. 
Interpro
 IPR003653; Peptidase_C48. 
Pfam
 PF02902; Peptidase_C48 
SMART
  
PROSITE
 PS50600; ULP_PROTEASE 
PRINTS