CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035575
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Glycine decarboxylase (Predicted), isoform CRA_a 
Protein Synonyms/Alias
 Protein Gldc 
Gene Name
 Gldc 
Gene Synonyms/Alias
 Gldc_predicted; rCG_48471 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
600IRAYLDQKGERHRTVacetylation[1]
628SAYMAGMKIQPVEVDacetylation[1]
646NIDVAHLKAMVDKHKacetylation[1]
706MMGGKGLKEATEIAIacetylation[1]
747ILDTRPFKKSANIEAacetylation[1]
841AFPLPFVKPENKFWPacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 884 AA 
Protein Sequence
MQLCARAWGL RLGPGAGGGH RLARGTGLSW APRSRDSSSG GGGGGGDRGA AGASRLLERL 60
LPRHDDFARR HIGPGDKDRR EMLQALGLAS IDELIEKTVP ASIRLKRPLK LEDPVCENEI 120
LETLHAIASK NQIWRSYIGM GYYNCSVPQT ILRNLLENSG WVTQYTPYQP EVSQGRLESL 180
LNYQTMVSDI TGLDMANASL LDEATAAAEA MQLCHRYRGV IVELKLPHEM DFSGKDVSGV 240
LFQYPDTEGK VEDFTELVER AHQTGSLTCC ATDLLALCIL RPPGEFGVDI ALGNSQRFGV 300
PLGYGGPHAA FFAVRESLVR MMPGRMVGVT RDATGKEVYR LALQTREQHI RRDKATSNIC 360
TAQALLANMA AMFAIYHGSH GLQHIAKRVH NATLILSEGL KRAGHQLQHD LFFDTLKVQC 420
GCSLKEVLGR AAQRQINFRL FDDGTLGISL DETVTEKDLD DLLWIFGCES STELVAEGMG 480
EEWRGLLGSS FKRTSPFLTH QVFNSYHSET NLVRYMKKLE NKDISLVHSM IPLPITWREF 540
ANIHPFVPLD QAQGYQQLFQ ELEKDLCELT GYDRVSFQPN SGAQGEYAGL ATIRAYLDQK 600
GERHRTVCLI PKSAHGTNPA SAYMAGMKIQ PVEVDRYGNI DVAHLKAMVD KHKENLAAIM 660
ITYPSTNGVF EENISDVCAL IHQHGGQVYL DGANMNAQMM GGKGLKEATE IAILNANYMA 720
KRLERYYRVL FRGYVAHEFI LDTRPFKKSA NIEAVDVAKR LQDYGTLMIE PTESEDKAEL 780
DRFCDAMISI RQEIADIEEG RIDPRVNPLK MSPHSLTCVT SSRWDRPYSR EVAAFPLPFV 840
KPENKFWPTI ARIDDIYGDQ HLVCTCPPME VYESPFSEQK RASS 884 
Gene Ontology
 GO:0005960; C:glycine cleavage complex; IDA:RGD.
 GO:0005739; C:mitochondrion; IDA:RGD.
 GO:0016594; F:glycine binding; IDA:RGD.
 GO:0004375; F:glycine dehydrogenase (decarboxylating) activity; IDA:RGD.
 GO:0016829; F:lyase activity; IEA:InterPro.
 GO:0046983; F:protein dimerization activity; IDA:RGD.
 GO:0030170; F:pyridoxal phosphate binding; IDA:RGD.
 GO:0019464; P:glycine decarboxylation via glycine cleavage system; IDA:RGD. 
Interpro
 IPR001597; ArAA_b-elim_lyase/Thr_aldolase.
 IPR020580; GDC-P_N.
 IPR020581; GDC_P.
 IPR015424; PyrdxlP-dep_Trfase.
 IPR015421; PyrdxlP-dep_Trfase_major_sub1. 
Pfam
 PF01212; Beta_elim_lyase
 PF02347; GDC-P 
SMART
  
PROSITE
  
PRINTS