CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030853
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Period circadian protein homolog 1 
Protein Synonyms/Alias
 cDNA FLJ59327, highly similar to Period circadian protein 1 
Gene Name
 PER1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
120SARARTQKELMTALRubiquitination[1]
279LRDFTQEKSVFCRIRubiquitination[1, 2]
308RLTPYVTKIRVSDGAubiquitination[1]
395LMLAIHKKILQLAGQubiquitination[1]
632CNLPSTTKRKCASSSubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 859 AA 
Protein Sequence
MLEVLEEIWS VRARRAHRPC PGPSLADDTD ANSNGSSGNE SNGHESRGAS QRSSHSSSSG 60
NGKDSALLET TESSKSTNSQ SPSPPSSSIA YSLLSASSEQ DNPSTSGCSS EQSARARTQK 120
ELMTALRELK LRLPPERRGK GRSGTLATLQ YALACVKQVQ ANQEYYQQWS LEEGEPCSMD 180
MSTYTLEELE HITSEYTLQN QDTFSVAVSF LTGRIVYISE QAAVLLRCKR DVFRGTRFSE 240
LLAPQDVGVF YGSTAPSRLP TWGTGASAGS GLRDFTQEKS VFCRIRGGPD RDPGPRYQPF 300
RLTPYVTKIR VSDGAPAQPC CLLIAERIHS GYEAPRIPPD KRIFTTRHTP SCLFQDVDER 360
AAPLLGYLPQ DLLGAPVLLF LHPEDRPLML AIHKKILQLA GQPFDHSPIR FCARNGEYVT 420
MDTSWAGFVH PWSRKVAFVL GRHKVRTAPL NEDVFTPPAP SPAPSLDTDI QELSEQIHRL 480
LLQPVHSPSP TGLCGVGAVT SPGPLHSPGS SSDSNGGDAE GPGPPAPVTF QQICKDVHLV 540
KHQGQQLFIE SRARPQSRPR LPATGTFKAK ALPCQSPDPE LEAGSAPVQA PLALVPEEAE 600
RKEASSCSYQ QINCLDSILR YLESCNLPST TKRKCASSSS YTTSSASDDD RQRTGPVSVG 660
TKKDPPSAAL SGEGATPRKE PVVGGTLSPL ALANKAESVV SVTSQCSFSS TIVHVGDKKP 720
PESDIIMMED LPGLAPGPAP SPAPSPTVAP DPAPDAYRPV GLTKAVLSLH TQKEEQAFLS 780
RFRDLGRLRG LDSSSTAPSA LGERGSHLGP PGACPLPSLG LDCWGVGLKG GVSAPGTQAG 840
VASTTRPCLG TGPSLASPH 859 
Gene Ontology
 GO:0004871; F:signal transducer activity; IEA:InterPro. 
Interpro
 IPR001610; PAC.
 IPR000014; PAS.
 IPR013655; PAS_fold_3. 
Pfam
 PF08447; PAS_3 
SMART
 SM00086; PAC
 SM00091; PAS 
PROSITE
 PS50112; PAS 
PRINTS