CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010777
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Geranylgeranyl transferase type-2 subunit alpha 
Protein Synonyms/Alias
 GGTase-II-alpha; Geranylgeranyl transferase type II subunit alpha; PGGT; Type II protein geranyl-geranyltransferase subunit alpha; YPT1/SEC4 proteins geranylgeranyltransferase subunit alpha 
Gene Name
 BET4 
Gene Synonyms/Alias
 YJL031C; J1254 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
50IYSIEALKKTSELLEubiquitination[1]
51YSIEALKKTSELLEKubiquitination[1]
Reference
 [1] Identification, analysis, and prediction of protein ubiquitination sites.
 Radivojac P, Vacic V, Haynes C, Cocklin RR, Mohan A, Heyen JW, Goebl MG, Iakoucheva LM.
 Proteins. 2010 Feb 1;78(2):365-80. [PMID: 19722269
Functional Description
 Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to proteins having the C-terminal -XCC or -XCXC, where both cysteines may become modified. Acts on YPT1 and SEC4. 
Sequence Annotation
 REPEAT 44 78 PFTA 1.
 REPEAT 84 118 PFTA 2.
 REPEAT 123 157 PFTA 3.
 REPEAT 163 197 PFTA 4.
 REPEAT 207 241 PFTA 5.  
Keyword
 Complete proteome; Prenyltransferase; Reference proteome; Repeat; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 327 AA 
Protein Sequence
MHGIKRKQWT KELLRQKRVQ DEKKIYDYRS LTENVLNMRD EKIYSIEALK KTSELLEKNP 60
EFNAIWNYRR DIIASLASEL EIPFWDKELV FVMMLLKDYP KVYWIWNHRL WVLKHYPTSS 120
PKVWQTELAV VNKLLEQDAR NYHGWHYRRI VVGNIESITN KSLDKEEFEY TTIKINNNIS 180
NYSAWHQRVQ IISRMFQKGE VGNQKEYIRT EISYIINAMF TDAEDQSVWF YIKWFIKNDI 240
VCKTLDEQEY LKMLKDLREN ILLINNDEIE FSGKQNIWCL KILLVLEDIL EEKEALTERS 300
SEQYLVQLID ADPLRKNRYL HLLEQHK 327 
Gene Ontology
 GO:0005968; C:Rab-protein geranylgeranyltransferase complex; IDA:SGD.
 GO:0004663; F:Rab geranylgeranyltransferase activity; IDA:SGD.
 GO:0006888; P:ER to Golgi vesicle-mediated transport; IMP:SGD.
 GO:0018344; P:protein geranylgeranylation; IDA:SGD.
 GO:0006612; P:protein targeting to membrane; IMP:SGD. 
Interpro
 IPR002088; Prenyl_trans_a. 
Pfam
 PF01239; PPTA 
SMART
  
PROSITE
 PS51147; PFTA 
PRINTS