CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015698
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Thymidine phosphorylase 
Protein Synonyms/Alias
 TdRPase 
Gene Name
 deoA 
Gene Synonyms/Alias
 STM4568 
Created Date
 July 27, 2013 
Organism
 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) 
NCBI Taxa ID
 99287 
Lysine Modification
Position
Peptide
Type
References
341LPTAMLSKAVYADTEacetylation[1]
Reference
 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 
Functional Description
 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; Glycosyltransferase; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 440 AA 
Protein Sequence
MFLAQEIIRK KRDGHALSDE EIRFFINGIR DNTISEGQIA ALAMTIFFHD MTMPERVSLT 60
MAMRDSGTVL DWKSLNLNGP IVDKHSTGGV GDVTSLMLGP MVAACGGYVP MISGRGLGHT 120
GGTLDKLEAI PGFDIFPDDN RFREIIQDVG VAIIGQTSSL APADKRFYAT RDITATVDSI 180
PLITGSILAK KLAEGLDALV MDVKVGSGAF MPTYELSEAL AEAIVGVANG AGVRTTALLT 240
DMNQVLASSA GNAVEVREAV QFLTGEYRNP RLFDVTMALC VEMLISGQLA KDDAEARAKL 300
QAVLDNGKAA EVFGRMVAAQ KGPSDFVENY DKYLPTAMLS KAVYADTEGF ISAMDTRALG 360
MAVVSMGGGR RQASDTIDYS VGFTDMARLG DSIDGQRPLA VIHAKDEASW QEAAKAVKAA 420
IILDDKAPAS TPSVYRRITE 440 
Gene Ontology
 GO:0004645; F:phosphorylase activity; IEA:InterPro.
 GO:0016154; F:pyrimidine-nucleoside phosphorylase activity; IEA:InterPro.
 GO:0009032; F:thymidine phosphorylase activity; IEA:EC.
 GO:0006206; P:pyrimidine nucleobase metabolic process; IEA:InterPro.
 GO:0006213; P:pyrimidine nucleoside metabolic process; IEA:InterPro. 
Interpro
 IPR000312; Glycosyl_Trfase_fam3.
 IPR017459; Glycosyl_Trfase_fam3_N_dom.
 IPR013102; PYNP_C.
 IPR018090; Pyrmidine_PPas_bac/euk.
 IPR000053; Pyrmidine_PPase.
 IPR017872; Pyrmidine_PPase_CS.
 IPR013465; Thymidine_Pase. 
Pfam
 PF02885; Glycos_trans_3N
 PF00591; Glycos_transf_3
 PF07831; PYNP_C 
SMART
 SM00941; PYNP_C 
PROSITE
 PS00647; THYMID_PHOSPHORYLASE 
PRINTS