| Tag | Content |
|---|
| CPLM ID | CPLM-020448 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Protein TANC1 |
Protein Synonyms/Alias | Tetratricopeptide repeat, ankyrin repeat and coiled-coil domain-containing protein 1 |
Gene Name | TANC1 |
Gene Synonyms/Alias | KIAA1728 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 566 | QDPVAAFKRGVLEPL | ubiquitination | [1] | | 804 | ALSCFLIKRRDKTRM | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | May be a scaffold component in the postsynaptic density (By similarity). |
Sequence Annotation | REPEAT 896 928 ANK 1.
REPEAT 934 963 ANK 2.
REPEAT 967 996 ANK 3.
REPEAT 1000 1029 ANK 4.
REPEAT 1040 1069 ANK 5.
REPEAT 1078 1107 ANK 6.
REPEAT 1111 1140 ANK 7.
REPEAT 1144 1173 ANK 8.
REPEAT 1177 1206 ANK 9.
REPEAT 1210 1239 ANK 10.
REPEAT 1243 1272 ANK 11.
REPEAT 1289 1322 TPR 1.
REPEAT 1336 1369 TPR 2.
REPEAT 1371 1403 TPR 3.
MOD_RES 66 66 Phosphoserine.
MOD_RES 207 207 Phosphoserine.
MOD_RES 1668 1668 Phosphoserine (By similarity). |
Keyword | Alternative splicing; ANK repeat; Cell junction; Cell membrane; Complete proteome; Membrane; Phosphoprotein; Polymorphism; Postsynaptic cell membrane; Reference proteome; Repeat; Synapse; TPR repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1861 AA |
Protein Sequence | MLKAVLKKSR EGGKGGKKEA GSDFGPETSP VLHLDHSADS PVSSLPTAED TYRVSLAKGV 60
SMSLPSSPLL PRQSHLVQSR VNKKSPGPVR KPKYVESPRV PGDAVIMPFR EVAKPTEPDE 120
HEAKADNEPS CSPAAQELLT RLGFLLGEGI PSATHITIED KNETMCTALS QGISPCSTLT 180
SSTASPSTDS PCSTLNSCVS KTAANKSPCE TISSPSSTLE SKDSGIIATI TSSSENDDRS 240
GSSLEWNKDG NLRLGVQKGV LHDRRADNCS PVAEEETTGS AESTLPKAES SAGDGPVPYS 300
QGSSSLIMPR PNSVAATSST KLEDLSYLDG QRNAPLRTSI RLPWHNTAGG RAQEVKARFA 360
PYKPQDILLK PLLFEVPSIT TDSVFVGRDW LFHQIEENLR NTELAENRGA VVVGNVGFGK 420
TAIISKLVAL SCHGSRMRQI ASNSPGSSPK TSDPTQDLHF TPLLSPSSST SASSTAKTPL 480
GSISAENQRP REDAVKYLAS KVVAYHYCQA DNTYTCLVPE FVHSIAALLC RSHQLAAYRD 540
LLIKEPQLQS MLSLRSCVQD PVAAFKRGVL EPLTNLRNEQ KIPEEEYIIL IDGLNEAEFH 600
KPDYGDTLSS FITKIISKFP AWLKLIVTVR ANFQEIISAL PFVKLSLDDF PDNKDIHSDL 660
HAYVQHRVHS SQDILSNISL NGKADATLIG KVSSHLVLRS LGSYLYLKLT LDLFQRGHLV 720
IKSASYKVVP VSLSELYLLQ CNMKFMTQSA FERALPILNV ALASLHPMTD EQIFQAINAG 780
HIQGEQGWED FQQRMDALSC FLIKRRDKTR MFCHPSFREW LVWRADGENT AFLCEPRNGH 840
ALLAFMFSRQ EGKLNRQQTM ELGHHILKAH IFKGLSKKTG ISSSHLQALW IGYSTEGLSA 900
ALASLRNLYT PNVKVSRLLI LGGANVNYRT EVLNNAPILC VQSHLGHEEV VTLLLEFGAC 960
LDGTSENGMT ALCYAAAAGH MKLVCLLTKK GVRVDHLDKK GQCALVHSAL RGHGDILQYL 1020
LTCEWSPGPP QPGTLRKSHA LQQALTAAAS MGHSSVVQCL LGMEKEHEVE VNGTDTLWGE 1080
TALTAAAGRG KLEVCELLLG HGAAVSRTNR RGVPPLFCAA RQGHWQIVRL LLERGCDVNL 1140
SDKQGRTPLM VAACEGHLST VEFLLSKGAA LSSLDKEGLS ALSWACLKGH RAVVQYLVEE 1200
GAAIDQTDKN GRTPLDLAAF YGDAETVLYL VEKGAVIEHV DHSGMRPLDR AIGCRNTSVV 1260
VALLRKGAKL GNAAWAMATS KPDILIILLQ KLMEEGNVMY KKGKMKEAAQ RYQYALRKFP 1320
REGFGEDMRP FNELRVSLYL NLSRCRRKTN DFGMAEEFAS KALELKPKSY EAFYARARAK 1380
RNSRQFVAAL ADLQEAVKLC PTNQEVKRLL ARVEEECKQL QRSQQQKQQG PLPAPLNDSE 1440
NEEDTPTPGL SDHFHSEETE EEETSPQEES VSPTPRSQPS SSVPSSYIRN LQEGLQSKGR 1500
PVSPQSRAGI GKSLREPVAQ PGLLLQPSKQ AQIVKTSQHL GSGQSAVRNG SMKVQISSQN 1560
PPPSPMPGRI AATPAGSRTQ HLEGTGTFTT RAGCGHFGDR LGPSQNVRLQ CGENGPAHPL 1620
PSKTKTTERL LSHSSVAVDA APPNQGGLAT CSDVRHPASL TSSGSSGSPS SSIKMSSSTS 1680
SLTSSSSFSD GFKVQGPDTR IKDKVVTHVQ SGTAEHRPRN TPFMGIMDKT ARFQQQSNPP 1740
SRSWHCPAPE GLLTNTSSAA GLQSANTEKP SLMQVGGYNN QAKTCSVSTL SASVHNGAQV 1800
KELEESKCQI PVHSQENRIT KTVSHLYQES ISKQQPHISN EAHRSHLTAA KPKRSFIESN 1860
V 1861 |
Gene Ontology | |
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