CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029528
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Kinesin light chain 3 
Protein Synonyms/Alias
  
Gene Name
 KLC2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
155NLAVLYGKRGKYKEAubiquitination[1]
239NLASCYLKQGKYQDAacetylation[2]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 521 AA 
Protein Sequence
MSQIRKLDED ASPNEEKGDV PKDTLDDLFP NEDEQSPAPS PGGGDVSGQH GGYEIPARLR 60
TLHNLVIQYA SQGRYEVAVP LCKQALEDLE KTSGHDHPDV ATMLNILALV YRDQNKYKEA 120
AHLLNDALAI REKTLGKDHP AVAATLNNLA VLYGKRGKYK EAEPLCKRAL EIREKVLGKF 180
HPDVAKQLSN LALLCQNQGK AEEVEYYYRR ALEIYATRLG PDDPNVAKTK NNLASCYLKQ 240
GKYQDAETLY KEILTRAHEK EFGSVNGDNK PIWMHAEERE ESKDKRRDSA PYGEYGSWYK 300
ACKVDSPTVN TTLRSLGALY RRQGKLEAAH TLEDCASRNR KQGLDPASQT KVVELLKDGS 360
GRRGDRRSSR DMAGGAGPRS ESDLEDVGPT AEWNGDGSGS LRRSGSFGKL RDALRRSSEM 420
LVKKLQGGTP QEPPNPRMKR ASSLNFLNKS VEEPTQVGAG GCLGTGQLRP GLHACCQASL 480
QHASSSSNSS WLCLRPTLGW TTGRHEGNPA SPGGGRVNGQ C 521 
Gene Ontology
 GO:0005871; C:kinesin complex; IEA:InterPro.
 GO:0003777; F:microtubule motor activity; IEA:InterPro. 
Interpro
 IPR002151; Kinesin_light.
 IPR015792; Kinesin_light_repeat.
 IPR015390; Rabaptin_Rab5-bd_dom.
 IPR013026; TPR-contain_dom.
 IPR011990; TPR-like_helical.
 IPR013105; TPR_2.
 IPR019734; TPR_repeat. 
Pfam
 PF09311; Rab5-bind
 PF07719; TPR_2 
SMART
 SM00028; TPR 
PROSITE
 PS01160; KINESIN_LIGHT
 PS50005; TPR
 PS50293; TPR_REGION 
PRINTS
 PR00381; KINESINLIGHT.