| Tag | Content |
|---|
| CPLM ID | CPLM-019196 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Constitutive coactivator of peroxisome proliferator-activated receptor gamma |
Protein Synonyms/Alias | Constitutive coactivator of PPAR-gamma; Constitutive coactivator of PPARG; PPARG constitutive coactivator 1; PGCC1; Protein FAM120B |
Gene Name | FAM120B |
Gene Synonyms/Alias | CCPG; KIAA1838 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 299 | PNKALFYKGMASYLL | ubiquitination | [1] | | 317 | KSPWFFQKPKGVITL | ubiquitination | [1] | | 836 | QNRSRLTKFHNLKAV | ubiquitination | [1] |
|
Reference | [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C. Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [ PMID: 21890473] |
Functional Description | Functions as a transactivator of PPARG and ESR1. Functions in adipogenesis through PPARG activation (By similarity). |
Sequence Annotation | |
Keyword | Activator; Alternative splicing; Complete proteome; Differentiation; Nucleus; Polymorphism; Reference proteome; Transcription; Transcription regulation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 910 AA |
Protein Sequence | MGVRGLQGFV GSTCPHICTV VNFKELAEHH RSKYPGCTPT IVVDAMCCLR YWYTPESWIC 60
GGQWREYFSA LRDFVKTFTA AGIKLIFFFD GMVEQDKRDE WVKRRLKNNR EISRIFHYIK 120
SHKEQPGRNM FFIPSGLAVF TRFALKTLGQ ETLCSLQEAD YEVASYGLQH NCLGILGEDT 180
DYLIYDTCPY FSISELCLES LDTVMLCREK LCESLGLCVA DLPLLACLLG NDIIPEGMFE 240
SFRYKCLSSY TSVKENFDKK GNIILAVSDH ISKVLYLYQG EKKLEEILPL GPNKALFYKG 300
MASYLLPGQK SPWFFQKPKG VITLDKQVIS TSSDAESREE VPMCSDAESR QEVPMCTGPE 360
SRREVPVYTD SEPRQEVPMC SDPEPRQEVP TCTGPESRRE VPMCSDPEPR QEVPMCTGPE 420
ARQEVPMYTD SEPRQEVPMY TDSEPRQEVP MYTGSEPRQE VPMYTGPESR QEVPMYTGPE 480
SRQEVLIRTD PESRQEIMCT GHESKQEVPI CTDPISKQED SMCTHAEINQ KLPVATDFEF 540
KLEALMCTNP EIKQEDPTNV GPEVKQQVTM VSDTEILKVA RTHHVQAESY LVYNIMSSGE 600
IECSNTLEDE LDQALPSQAF IYRPIRQRVY SLLLEDCQDV TSTCLAVKEW FVYPGNPLRH 660
PDLVRPLQMT IPGGTPSLKI LWLNQEPEIQ VRRLDTLLAC FNLSSSREEL QAVESPFQAL 720
CCLLIYLFVQ VDTLCLEDLH AFIAQALCLQ GKSTSQLVNL QPDYINPRAV QLGSLLVRGL 780
TTLVLVNSAC GFPWKTSDFM PWNVFDGKLF HQKYLQSEKG YAVEVLLEQN RSRLTKFHNL 840
KAVVCKACMK ENRRITGRAH WGSHHAGRWG RQGSSYHRTG SGYSRSSQGQ PWRDQGPGSR 900
QYEHDQWRRY 910 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0030154; P:cell differentiation; IEA:UniProtKB-KW. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |