UniProt Accession

 GLYG_HUMAN; P46976; D3DNH0; D3DNH1; D3DNH2; Q6FHZ1; Q9UNV0 

Genbank Protein ID

 U44131; U31525; X79537; AF065481; AF065476; AF065477; AF065478; AF065479; AF065480; AF087942; CR536547; AC021059; CH471052; CH471052; CH471052; CH471052; CH471052; CH471052; BC000033 

Genbank Nucleotide ID

 AAB00114.1; AAB09752.1; CAA56073.1; AAD31084.1; AAD31084.1; AAD31084.1; AAD31084.1; AAD31084.1; AAD31084.1; AAD52093.1; CAG38784.1; EAW78894.1; EAW78895.1; EAW78896.1; EAW78898.1; EAW78900.1; EAW78901.1; AAH00033.1 

Protein Name

 Glycogenin-1 

Protein Synonyms/Alias

 GN-1; GN1 

Gene Name

 GYG1 

Gene Synonyms/Alias

 GYG 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
209	KVFGASAKVVHFLGR	ubiquitination	[1, 2]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

 Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase. 

Sequence Annotation

 REGION 301 333 Interaction with GYS1.
 ACT_SITE 86 86 By similarity.
 METAL 102 102 Manganese (By similarity).
 METAL 104 104 Manganese (By similarity).
 METAL 212 212 Manganese (By similarity).
 MOD_RES 2 2 N-acetylthreonine.
 MOD_RES 44 44 Phosphoserine (By similarity).
 CARBOHYD 195 195 O-linked (Glc...) (By similarity).  

Keyword

 3D-structure; Acetylation; Alternative splicing; Complete proteome; Disease mutation; Glycogen biosynthesis; Glycogen storage disease; Glycoprotein; Manganese; Metal-binding; Phosphoprotein; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 350 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; TAS:Reactome.
 GO:0005536; F:glucose binding; IEA:Compara.
 GO:0008466; F:glycogenin glucosyltransferase activity; IEA:EC.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0006006; P:glucose metabolic process; TAS:Reactome.
 GO:0005978; P:glycogen biosynthetic process; TAS:Reactome.
 GO:0005980; P:glycogen catabolic process; TAS:Reactome.
 GO:0044281; P:small molecule metabolic process; TAS:Reactome. 

Interpro

 IPR002495; Glyco_trans_8. 

Pfam

 PF01501; Glyco_transf_8 

SMART

  

PROSITE

  

PRINTS