CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033953
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Proliferation-associated protein 2G4 
Protein Synonyms/Alias
  
Gene Name
 Pa2g4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
22DLVVTKYKMGGDIANubiquitination[1]
93SDQDYILKEGDLVKIacetylation[2]
150EAALRLVKPGNQNTQubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Hydrolase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 275 AA 
Protein Sequence
MSGEDEQQEQ TIAEDLVVTK YKMGGDIANR VLRSLVEASS SGVSVLSLCE KGDAMIMEET 60
GKIFKKEKEM KKGIAFPTSI SVNNCSDQDY ILKEGDLVKI DLGVHVDGFI ANVAHTFVIG 120
VAQGTQVTGR KADVIKAAHL CAEAALRLVK PGNQNTQVTE AWNKVAHSFN CTPIEGMLSH 180
QLKQHVIDGE KTIIQNPTDQ QKKDHEKAEF ERDPSKQYGL KMKTSRAFFS EVERRFDAMP 240
FTLRAFEDEK KARMGVVECA KHELLQPFNV LYEKE 275 
Gene Ontology
 GO:0005634; C:nucleus; ISA:MGI.
 GO:0030529; C:ribonucleoprotein complex; ISO:MGI.
 GO:0003677; F:DNA binding; ISA:MGI.
 GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISA:MGI.
 GO:0009987; P:cellular process; IEA:InterPro.
 GO:0045892; P:negative regulation of transcription, DNA-dependent; ISA:MGI. 
Interpro
 IPR000994; Pept_M24_structural-domain.
 IPR018349; Pept_M24A_MAP2_BS.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF00557; Peptidase_M24 
SMART
  
PROSITE
 PS01202; MAP_2 
PRINTS