CPLM 1.0 - Compendium of Protein Lysine Modification
Tag
Content
CPLM ID
CPLM-017523
UniProt Accession
ANR42_HUMAN
;
Q8N9B4
;
Q49A49
Genbank Protein ID
AK095193
;
BC045621
Genbank Nucleotide ID
BAC04496.1
;
AAH45621.1
Protein Name
Ankyrin repeat domain-containing protein 42
Protein Synonyms/Alias
Gene Name
ANKRD42
Gene Synonyms/Alias
Created Date
July 27, 2013
Organism
Homo sapiens (Human)
NCBI Taxa ID
9606
Lysine Modification
Position
Peptide
Type
References
40
AVRAGDV
K
QLSEIVC
ubiquitination
[1]
129
VDPSVTD
K
REWRPVH
ubiquitination
[1]
Reference
[1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
Mol Cell. 2011 Oct 21;44(2):325-40. [
PMID: 21906983
]
Functional Description
Sequence Annotation
REPEAT 25 60 ANK 1.
REPEAT 64 93 ANK 2.
REPEAT 97 126 ANK 3.
REPEAT 130 159 ANK 4.
REPEAT 163 192 ANK 5.
REPEAT 200 232 ANK 6.
REPEAT 235 265 ANK 7.
REPEAT 269 298 ANK 8.
REPEAT 302 332 ANK 9.
Keyword
Alternative splicing; ANK repeat; Complete proteome; Polymorphism; Reference proteome; Repeat.
Sequence Source
UniProt (SWISSPROT/TrEMBL); GenBank; EMBL
Protein Length
389 AA
Protein Sequence
MPGVANSGPS TSSRETANPC SRKKVHFGSI HDAVRAGDVK QLSEIVCLHW LLWHGADITH 60
VTTRGWTASH IAAIRGQDAC VQALIMNGAN LTAQDDRGCT PLHLAATHGH SFTLQIMLRS 120
GVDPSVTDKR EWRPVHYAAF HGRLGCLQLL VKWGCSIEDV DYNGNLPVHL AAMEGHLHCF 180
KFLVSRMSSA TQVLKAFNDN GENVLDLAQR FFKQNILQFI QGAEYEGKDL EDQETLAFPG 240
HVAAFKGDLG MLKKLVEDGV ININERADNG STPMHKAAGQ GHIECLQWLI KMGADSNITN 300
KAGERPSDVA KRFAHLAAVK LLEELQKYDI DDENEIDEND VKYFIRHGVE GSTDAKDDLC 360
LSDLDKTDAR RPSKNCRASW SMNDYVEKN 389
Gene Ontology
GO:0005634
; C:nucleus; IEA:Compara.
GO:1900017
; P:positive regulation of cytokine production involved in inflammatory response; IEA:Compara.
GO:0051092
; P:positive regulation of NF-kappaB transcription factor activity; IEA:Compara.
Interpro
IPR002110
; Ankyrin_rpt.
IPR020683
; Ankyrin_rpt-contain_dom.
IPR018247
; EF_Hand_1_Ca_BS.
Pfam
PF12796
; Ank_2
SMART
SM00248
; ANK
PROSITE
PS50297
; ANK_REP_REGION
PS50088
; ANK_REPEAT
PRINTS
PR01415
; ANKYRIN.