UniProt Accession

 RISA_ECOLI; P0AFU8; P29015 

Genbank Protein ID

 X69109; U68703; U00096; AP009048 

Genbank Nucleotide ID

 CAA48861.1; AAB47940.1; AAC74734.1; BAA15429.1 

Protein Name

 Riboflavin synthase 

Protein Synonyms/Alias

 RS 

Gene Name

 ribC 

Gene Synonyms/Alias

 ribE; b1662; JW1654 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
18	KLVSIDEKPNFRTHV	acetylation	[1]
77	ITNLGDLKVGDWVNV	acetylation	[1]
89	VNVERAAKFSDEIGG	acetylation	[1]
111	MTTAEVAKILTSENN	acetylation	[1]
124	NNRQIWFKVQDSQLM	acetylation	[1]
132	VQDSQLMKYILYKGF	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 Catalyzes the dismutation of two molecules of 6,7- dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil. 

Sequence Annotation

 REPEAT 1 97 Lumazine-binding 1.
 REPEAT 98 195 Lumazine-binding 2.
 REGION 4 6 Substrate binding.
 REGION 48 50 Substrate binding.
 REGION 62 67 Substrate binding.  

Keyword

 3D-structure; Complete proteome; Reference proteome; Repeat; Riboflavin biosynthesis; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 213 AA 

Protein Sequence

Gene Ontology

 GO:0016491; F:oxidoreductase activity; IEA:InterPro.
 GO:0004746; F:riboflavin synthase activity; IDA:EcoCyc.
 GO:0009231; P:riboflavin biosynthetic process; IDA:EcoCyc. 

Interpro

 IPR023366; ATPase_F1/A1-cplx_a_su_N.
 IPR001783; Lumazine-bd.
 IPR026017; Lumazine-bd_dom.
 IPR017938; Riboflavin_synthase-like_b-brl. 

Pfam

 PF00677; Lum_binding 

SMART

  

PROSITE

 PS51177; LUMAZINE_BIND 

PRINTS