CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041919
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Oxysterol-binding protein 
Protein Synonyms/Alias
  
Gene Name
 Osbpl11 
Gene Synonyms/Alias
 mCG_130137 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
406LPTFILEKRSLLEMYubiquitination[1]
458RKGAIAKKPYNPIIGacetylation[2]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Lipid transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 757 AA 
Protein Sequence
MNFGVKMQGG EPASVMKVSE SEGKLEGLAT AVTPNKNSGN SSCGGAISSS SSNSSRGGSA 60
KGWQYSDHME SVNGYLMKYT NLVTGWQYRF FVLNNEAGLL EYFVNEQSRN QKPRGTLQLA 120
GAVISPSDED SHTFTVNAAS GEQYKLRATD AKERQHWVSR LQICTQHHTE AIGKNNPPLK 180
SRSFSLASSG NSPISQRRPS QNAMSFFNVG HSKLQSVNKR AHLHPDHLVE VREMMSHAEG 240
QQRDLIRRIE CLPASGLLSS LDQDLLMLKA TSMATMNCLN DCFHILQLQH ASHQKGALPS 300
GTTIEWLEPK IPLSNHYKNG AEQPFATEPN KPMGAPEAQC VAESGVLARE PEDINADDEV 360
EDTCDNKEDD LGAVEEQRSV ILHLLSQLKL GMDLTRVVLP TFILEKRSLL EMYADFMSHP 420
DLFIGITNGA TPEDRMIRFV EYYLTSFHEG RKGAIAKKPY NPIIGETFHC SWRMPKSEVA 480
SGVSSSSSTP AITDHAPLPE EAPTQSVSDC YTVRFVAEQV SHHPPVSGFY AECAERKMCV 540
NAHVWTKSKF LGMSIGVTMV GEGVLCLLEH GEEYTFSLPC AYARSILTVP WVELGGKVSV 600
NCAKTGYSAS ITFHTKPFYG GKLHRVTAEV KYNLTNTVVC RVQGEWNSVL EFTYSNGETK 660
FVDLAKLAVT KKRVRPLEKQ DPFESRRLWK NVTDSLRESE IDKATEHKRS LEERQRTEER 720
LRTETGTPWK TKYFIKEGDG WVYHKPLWKG IPSQPAE 757 
Gene Ontology
 GO:0005543; F:phospholipid binding; IEA:InterPro.
 GO:0045444; P:fat cell differentiation; IEA:Compara.
 GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
 GO:0010890; P:positive regulation of sequestering of triglyceride; IEA:Compara. 
Interpro
 IPR000648; Oxysterol-bd.
 IPR018494; Oxysterol-bd_CS.
 IPR011993; PH_like_dom.
 IPR001849; Pleckstrin_homology. 
Pfam
 PF01237; Oxysterol_BP
 PF00169; PH 
SMART
 SM00233; PH 
PROSITE
 PS01013; OSBP
 PS50003; PH_DOMAIN 
PRINTS