CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032140
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Lysosomal Pro-X carboxypeptidase 
Protein Synonyms/Alias
 cDNA FLJ57232, highly similar to Lysosomal Pro-X carboxypeptidase (EC3.4.16.2) 
Gene Name
 PRCP 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
32PFGDNSFKDSRHLNFubiquitination[1, 2]
357HHLDLRTKNALDPMSubiquitination[1, 2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094] 
Functional Description
  
Sequence Annotation
  
Keyword
 Carboxypeptidase; Complete proteome; Hydrolase; Protease; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 391 AA 
Protein Sequence
MWDVAEELKA MLVFAEHRYY GESLPFGDNS FKDSRHLNFL TSEQALADFA ELIKHLKRTI 60
PGAENQPVIA IGGSYGGMLA AWFRMKYPHM VVGALAASAP IWQFEDLVPC GVFMKIVTTD 120
FRKSGPHCSE SIHRSWDAIN RLSNTGSGLQ WLTGALHLCS PLTSQDIQHL KDWISETWVN 180
LAMVDYPYAS NFLQPLPAWP IKVVCQYLKN PNVSDSLLLQ NIFQALNVYY NYSGQVKCLN 240
ISETATSSLG TLGWSYQACT EVVMPFCTNG VDDMFEPHSW NLKELSDDCF QQWGVRPRPS 300
WITTMYGGKN ISSHTNIVFS NGELDPWSGG GVTKDITDTL VAVTISEGAH HLDLRTKNAL 360
DPMSVLLARS LEVRHMKNWI RDFYDSAGKQ H 391 
Gene Ontology
 GO:0004180; F:carboxypeptidase activity; IEA:UniProtKB-KW.
 GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
 GO:0006508; P:proteolysis; IEA:InterPro. 
Interpro
 IPR008758; Peptidase_S28. 
Pfam
 PF05577; Peptidase_S28 
SMART
  
PROSITE
  
PRINTS