UniProt Accession

 SRP19_HUMAN; P09132; B2R4E9; D6RCQ5; Q05D77; Q96FG6 

Genbank Protein ID

 X12791; BU661702; AK311803; AC008536; AC008575; CH471086; CH471086; BC010947; BC017830 

Genbank Nucleotide ID

 CAA31280.1; BAG34746.1; EAW48999.1; EAW49000.1; AAH10947.1; AAH17830.1 

Protein Name

 Signal recognition particle 19 kDa protein 

Protein Synonyms/Alias

 SRP19 

Gene Name

 SRP19 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
102	LVQFPSRKSVMLYAA	ubiquitination	[1]
121	KLKTRTQKTGGADQS	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

 Signal-recognition-particle assembly, binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP. 

Sequence Annotation

 REGION 136 144 Basic region, potentially involved in
 MOD_RES 2 2 N-acetylalanine.  

Keyword

 3D-structure; Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Direct protein sequencing; Polymorphism; Reference proteome; Ribonucleoprotein; RNA-binding; Signal recognition particle. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 144 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; TAS:Reactome.
 GO:0005739; C:mitochondrion; IDA:HPA.
 GO:0005730; C:nucleolus; IDA:MGI.
 GO:0005786; C:signal recognition particle, endoplasmic reticulum targeting; IDA:UniProtKB.
 GO:0008312; F:7S RNA binding; IDA:UniProtKB.
 GO:0042493; P:response to drug; IDA:UniProtKB.
 GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
 GO:0006412; P:translation; TAS:Reactome. 

Interpro

 IPR002778; Signal_recog_particle_SRP19. 

Pfam

 PF01922; SRP19 

SMART

  

PROSITE

  

PRINTS