CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010214
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Uncharacterized HTH-type transcriptional regulator YciT 
Protein Synonyms/Alias
  
Gene Name
 yciT 
Gene Synonyms/Alias
 b1284; JW1276 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
43QDLNTLEKLSYLRRAacetylation[1]
73MMSNYTLKRELAEFAacetylation[1]
109ARTLGEQKKNVTIITacetylation[1]
228NRVITDSKIRASDLMacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
  
Sequence Annotation
 DOMAIN 1 56 HTH deoR-type.
 DNA_BIND 18 37 H-T-H motif (Potential).  
Keyword
 Complete proteome; DNA-binding; Reference proteome; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 249 AA 
Protein Sequence
MNSRQQTILQ MVIDQGQVSV TDLAKATGVS EVTIRQDLNT LEKLSYLRRA HGFAVSLDSD 60
DVETRMMSNY TLKRELAEFA ASLVQPGETI FIENGSSNAL LARTLGEQKK NVTIITVSSY 120
IAHLLKDAPC EVILLGGVYQ KKSESMVGPL TRQCIQQVHF SKAFIGIDGW QPETGFTGRD 180
MMRTDVVNAV LEKECEAIVL TDSSKFGAVH SYSIGPVERF NRVITDSKIR ASDLMHLEHS 240
KLTIHVVDI 249 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0006974; P:response to DNA damage stimulus; IEP:EcoliWiki.
 GO:0006351; P:transcription, DNA-dependent; EXP:EcoCyc. 
Interpro
 IPR014036; DeoR_C.
 IPR001034; HTH_DeoR_N.
 IPR018356; Tscrpt_reg_HTH_DeoR_CS.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF00455; DeoRC
 PF08220; HTH_DeoR 
SMART
 SM00420; HTH_DEOR 
PROSITE
 PS00894; HTH_DEOR_1
 PS51000; HTH_DEOR_2 
PRINTS
 PR00037; HTHLACR.