UniProt Accession

 FAIM1_HUMAN; Q9NVQ4; Q6IAN2 

Genbank Protein ID

 AK001444; AK125477; CR457122; AC020890; BC012478; BQ638715 

Genbank Nucleotide ID

 BAA91695.1; BAC86174.1; CAG33403.1; AAH12478.1 

Protein Name

 Fas apoptotic inhibitory molecule 1 

Protein Synonyms/Alias

  

Gene Name

 FAIM 

Gene Synonyms/Alias

 FAIM1 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
47	IRKEWMFKLVGKETF	ubiquitination	[1]
160	AVSSGKRKEGIIHTL	ubiquitination	[1]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 

Functional Description

 Plays a role as an inducible effector molecule that mediates Fas resistance produced by surface Ig engagement in B cells (By similarity). 

Sequence Annotation

 MOD_RES 2 2 N-acetylthreonine.  

Keyword

 3D-structure; Acetylation; Alternative splicing; Apoptosis; Complete proteome; Cytoplasm; Polymorphism; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 179 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
 GO:0043066; P:negative regulation of apoptotic process; IEA:InterPro. 

Interpro

 IPR010695; FAIM. 

Pfam

 PF06905; FAIM1 

SMART

  

PROSITE

  

PRINTS