UniProt Accession

 KAD_GEOKA; Q5L3R8 

Genbank Protein ID

 BA000043 

Genbank Nucleotide ID

 BAD74412.1 

Protein Name

 Adenylate kinase 

Protein Synonyms/Alias

 AK; ATP-AMP transphosphorylase; ATP:AMP phosphotransferase; Adenylate monophosphate kinase 

Gene Name

 adk 

Gene Synonyms/Alias

 GK0127 

Created Date

 July 27, 2013 

Organism

 Geobacillus kaustophilus (strain HTA426) 

NCBI Taxa ID

 235909 

Lysine Modification

Position	Peptide	Type	References
19	GKGTQAGKIVEAYGI	acetylation	[1]

Reference

 [1] Proteomic analysis of acetylation in thermophilic Geobacillus kaustophilus.
 Lee DW, Kim D, Lee YJ, Kim JA, Choi JY, Kang S, Pan JG.
 Proteomics. 2013 Aug;13(15):2278-82. [PMID: 23696451] 

Functional Description

 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity). 

Sequence Annotation

 NP_BIND 10 15 ATP (By similarity).
 NP_BIND 57 59 AMP (By similarity).
 NP_BIND 85 88 AMP (By similarity).
 NP_BIND 136 137 ATP (By similarity).
 REGION 30 59 NMPbind (By similarity).
 REGION 126 163 LID (By similarity).
 METAL 130 130 Zinc; structural (By similarity).
 METAL 133 133 Zinc; structural (By similarity).
 METAL 150 150 Zinc; structural (By similarity).
 METAL 153 153 Zinc; structural (By similarity).
 BINDING 31 31 AMP (By similarity).
 BINDING 36 36 AMP (By similarity).
 BINDING 92 92 AMP (By similarity).
 BINDING 127 127 ATP (By similarity).
 BINDING 160 160 AMP (By similarity).
 BINDING 171 171 AMP (By similarity).
 BINDING 199 199 ATP; via carbonyl oxygen (By similarity).  

Keyword

 ATP-binding; Complete proteome; Cytoplasm; Kinase; Metal-binding; Nucleotide biosynthesis; Nucleotide-binding; Transferase; Zinc. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 217 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0004017; F:adenylate kinase activity; IEA:HAMAP.
 GO:0005524; F:ATP binding; IEA:HAMAP.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0044209; P:AMP salvage; IEA:UniProtKB-UniPathway. 

Interpro

 IPR006259; Adenyl_kin_sub.
 IPR000850; Adenylate_kin.
 IPR007862; Adenylate_kinase_lid-dom.
 IPR027417; P-loop_NTPase. 

Pfam

 PF00406; ADK
 PF05191; ADK_lid 

SMART

  

PROSITE

 PS00113; ADENYLATE_KINASE 

PRINTS

 PR00094; ADENYLTKNASE.