UniProt Accession

 H0Y999_HUMAN; H0Y999 

Genbank Protein ID

 AC104116 

Genbank Nucleotide ID

  

Protein Name

 M-phase inducer phosphatase 3 

Protein Synonyms/Alias

  

Gene Name

 CDC25C 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
46	KYFSGQGKLRKGLCL	ubiquitination	[1]
55	RKGLCLKKTVSLCDI	ubiquitination	[1]
83	HLIGDFSKVCALPTV	ubiquitination	[2]
93	ALPTVSGKHQDLKYV	ubiquitination	[1]
162	LFNFFLKKPIVPLDT	ubiquitination	[1]
215	YPELYILKGGYRDFF	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 258 AA 

Protein Sequence

Gene Ontology

 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
 GO:0035335; P:peptidyl-tyrosine dephosphorylation; IEA:GOC. 

Interpro

 IPR000751; MPI_Phosphatase.
 IPR001763; Rhodanese-like_dom. 

Pfam

 PF06617; M-inducer_phosp
 PF00581; Rhodanese 

SMART

 SM00450; RHOD 

PROSITE

 PS50206; RHODANESE_3 

PRINTS

 PR00716; MPIPHPHTASE.