CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013742
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 DNA-directed RNA polymerase subunit beta 
Protein Synonyms/Alias
 RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta 
Gene Name
 rpoB 
Gene Synonyms/Alias
 GK0098 
Created Date
 July 27, 2013 
Organism
 Geobacillus kaustophilus (strain HTA426) 
NCBI Taxa ID
 235909 
Lysine Modification
Position
Peptide
Type
References
701RLIEVDGKEVKGDLDacetylation[1]
981LHLGMAAKKLGLHIAacetylation[1]
Reference
 [1] Proteomic analysis of acetylation in thermophilic Geobacillus kaustophilus.
 Lee DW, Kim D, Lee YJ, Kim JA, Choi JY, Kang S, Pan JG.
 Proteomics. 2013 Aug;13(15):2278-82. [PMID: 23696451] 
Functional Description
 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; DNA-directed RNA polymerase; Nucleotidyltransferase; Transcription; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1190 AA 
Protein Sequence
MTGRLVQYGR HRQRRSYARI SEVLELPNLI EIQTSSYQWF LDEGLREMFR EISPIEDFSG 60
NLSLEFIDYS LGEPKYTVEE AKERDVTYAA PLRVKVRLIN KETGEVKEQD VFMGDFPLMT 120
ETGTFIINGA ERVIVSQLVR SPSVYYSDKV DKNGKRGYSA TVIPNRGAWL EYETDAKDVV 180
YVRIDRTRKL PVTVLLRALG FSSDQEIIDL LGDNEYLRNT LEKDNTDSTE KALIEIYERL 240
RPGEPPTLEN AKNLLASRFF DPKRYDLASV GRYKINKKLH IKNRLFNQRL AETIIDPETK 300
EVIAEAGAMI DRRTLNRLLP YLEKGVGLQT YRPAEGVVDG DISVQTIKIY APNDPDGEKV 360
INVIGNGFIA EDVKHITPAD IIASISYFFN LLHGVGDTDD IDHLGNRRLR SVGELLQNQF 420
RIGLSRMERV VRERMSIQDT NTITPQQLIN IRPVIAAIKE FFGSSQLSQF MDQTNPLAEL 480
THKRRLSALG PGGLTRERAG FEVRDVHYSH YGRMCPIETP EGPNIGLINS LSTYAKVNKF 540
GFIETPYRRV DPETGRVTDQ IDYLTADEED NYVVAQANVP LAEDGTFLEE NVVARFRGEN 600
IVVKRDRVDY MDVSPKQVVS AATACIPFLE NDDSNRALMG ANMQRQAVPL LEPEAPIVGT 660
GMEYVSAKDS GAAVICKHRG IVERVEAKEI WVRRLIEVDG KEVKGDLDKY RLLKFVRSNQ 720
GTCYNQRPIV KKGDIVEKGE ILADGPSMDK GELALGRNVL VAFMTWDGYN YEDAIIMSER 780
LVKEDVYTSI HIEEYEAESR DTKLGPEEIT RDIPNVGEDA LKNLDERGIV RIGAEVKDGD 840
LLVGKVTPKG MTELTAEERL LHAIFGEKAR EVRDTSLRVP HGGGGIVLDV KVFNREDGDE 900
LPPGVNQLVR VYIVQKRKIS EGDKMAGRHG NKGVISRILP EEDMPFLPDG TPIDIMLNPL 960
GVPSRMNIGQ VFELHLGMAA KKLGLHIASP VFDGATEEDV WNILEEAGLA RDAKTVLYDG 1020
RTGEPFDNRV SVGIMYMIKL AHMVDDKLHA RSTGPYSLVT QQPLGGKAQF GGQRFGEMEV 1080
WALEAYGAAY TLQEILTVKS DDVVGRVKTY EAIVKGENIP EPGVPESFKV LIKELQSLGM 1140
DVTILTSDEQ EVNMENFDDD DDHAPDAIMV DVKPAEREEA GEEKDAVTKE 1190 
Gene Ontology
 GO:0003677; F:DNA binding; IEA:HAMAP.
 GO:0003899; F:DNA-directed RNA polymerase activity; IEA:HAMAP.
 GO:0032549; F:ribonucleoside binding; IEA:InterPro.
 GO:0006351; P:transcription, DNA-dependent; IEA:HAMAP. 
Interpro
 IPR010243; DNA-dir_RNA_pol_bsu.
 IPR019462; DNA-dir_RNA_pol_bsu_external_1.
 IPR015712; DNA-dir_RNA_pol_su2.
 IPR007120; DNA-dir_RNA_pol_su2_6.
 IPR007121; RNA_pol_bsu_CS.
 IPR007644; RNA_pol_bsu_protrusion.
 IPR007642; RNA_pol_Rpb2_2.
 IPR007645; RNA_pol_Rpb2_3.
 IPR007641; RNA_pol_Rpb2_7.
 IPR014724; RNA_pol_RPB2_OB-fold. 
Pfam
 PF04563; RNA_pol_Rpb2_1
 PF04561; RNA_pol_Rpb2_2
 PF04565; RNA_pol_Rpb2_3
 PF10385; RNA_pol_Rpb2_45
 PF00562; RNA_pol_Rpb2_6
 PF04560; RNA_pol_Rpb2_7 
SMART
  
PROSITE
 PS01166; RNA_POL_BETA 
PRINTS