UniProt Accession

 RPAC2_YEAST; P28000; D6W168 

Genbank Protein ID

 M64991; Z69382; Z71390; AY558001; BK006947 

Genbank Nucleotide ID

 AAA34998.1; CAA93394.1; CAA95994.1; AAS56327.1; DAA10434.1 

Protein Name

 DNA-directed RNA polymerases I and III subunit RPAC2 

Protein Synonyms/Alias

 RNA polymerases I and III subunit AC2; AC19; DNA-directed RNA polymerases I and III 16 kDa polypeptide; RPA19 

Gene Name

 RPC19 

Gene Synonyms/Alias

 YNL113W; N1937 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
9	TEDIEQKKTATEVTP	ubiquitination	[1]
82	ALRYVIMKNPDVEFC	ubiquitination	[1]
119	TAVDALQKGLKDLMD	ubiquitination	[1, 2]
134	LCDVVESKFTEKIKS	ubiquitination	[2]

Reference

 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047] 

Functional Description

 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common core component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively. 

Sequence Annotation

 MOD_RES 15 15 Phosphothreonine.
 MOD_RES 33 33 Phosphothreonine.  

Keyword

 Complete proteome; Direct protein sequencing; DNA-directed RNA polymerase; Nucleus; Phosphoprotein; Reference proteome; Transcription. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 142 AA 

Protein Sequence

Gene Ontology

 GO:0005736; C:DNA-directed RNA polymerase I complex; IDA:SGD.
 GO:0005666; C:DNA-directed RNA polymerase III complex; IDA:SGD.
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
 GO:0006360; P:transcription from RNA polymerase I promoter; IDA:SGD.
 GO:0042797; P:tRNA transcription from RNA polymerase III promoter; IDA:SGD. 

Interpro

 IPR009025; DNA-dir_RNA_pol_RBP11-like.
 IPR008193; RNA_pol_Rpb11_13-16kDa_CS. 

Pfam

  

SMART

  

PROSITE

 PS01154; RNA_POL_L_13KD 

PRINTS