CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006254
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Eukaryotic translation initiation factor eIF-1 
Protein Synonyms/Alias
 Protein translation factor SUI1 
Gene Name
 SUI1 
Gene Synonyms/Alias
 RFR1; YNL244C; N0905 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
37IQQRNGRKTLTTVQGubiquitination[1]
52VPEEYDLKRILKVLKacetylation[2]
52VPEEYDLKRILKVLKubiquitination[1]
60RILKVLKKDFACNGNacetylation[2]
70ACNGNIVKDPEMGEIubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919
Functional Description
 Additional factor that functions in concert with eIF-2 and the initiator tRNA in directing the ribosome to the proper start site of translation. 
Sequence Annotation
  
Keyword
 3D-structure; Complete proteome; Protein biosynthesis; Reference proteome; Translation regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 108 AA 
Protein Sequence
MSIENLKSFD PFADTGDDET ATSNYIHIRI QQRNGRKTLT TVQGVPEEYD LKRILKVLKK 60
DFACNGNIVK DPEMGEIIQL QGDQRAKVCE FMISQLGLQK KNIKIHGF 108 
Gene Ontology
 GO:0043614; C:multi-eIF complex; IDA:SGD.
 GO:0003743; F:translation initiation factor activity; TAS:SGD.
 GO:0006417; P:regulation of translation; IEA:UniProtKB-KW. 
Interpro
 IPR005874; SUI1_euk.
 IPR001950; TIF_SUI1. 
Pfam
 PF01253; SUI1 
SMART
  
PROSITE
 PS50296; SUI1 
PRINTS