UniProt Accession

 SSB_ECOLI; P0AGE0; P02339; Q2M6P5 

Genbank Protein ID

 J01704; U00006; U00096; AP009048 

Genbank Nucleotide ID

 AAA24649.1; AAC43153.1; AAC77029.1; BAE78061.1 

Protein Name

 Single-stranded DNA-binding protein 

Protein Synonyms/Alias

 SSB; Helix-destabilizing protein 

Gene Name

 ssb 

Gene Synonyms/Alias

 exrB; lexC; b4059; JW4020 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
8	MASRGVNKVILVGNL	acetylation	[1]
44	TSESWRDKATGEMKE	acetylation	[1, 2]
50	DKATGEMKEQTEWHR	acetylation	[1, 2]
63	HRVVLFGKLAEVASE	acetylation	[1, 2, 3, 4]
74	VASEYLRKGSQVYIE	acetylation	[1]
88	EGQLRTRKWTDQSGQ	acetylation	[1, 2]

Reference

 [1] The role of the 6 lysines and the terminal amine of Escherichia coli single-strand binding protein in its binding of single-stranded DNA.
 Chen J, Smith DL, Griep MA.
 Protein Sci. 1998 Aug;7(8):1781-8. [PMID: 10082375]
 [2] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618]
 [3] The diversity of lysine-acetylated proteins in Escherichia coli.
 Yu BJ, Kim JA, Moon JH, Ryu SE, Pan JG.
 J Microbiol Biotechnol. 2008 Sep;18(9):1529-36. [PMID: 18852508]
 [4] Comprehensive profiling of protein lysine acetylation in Escherichia coli.
 Zhang K, Zheng S, Yang JS, Chen Y, Cheng Z.
 J Proteome Res. 2013 Feb 1;12(2):844-51. [PMID: 23294111] 

Functional Description

 This protein is essential for replication of the chromosomes and its single-stranded DNA phages. It is also involved in DNA recombination and repair. 

Sequence Annotation

 DOMAIN 6 111 SSB.
 DNA_BIND 55 61  

Keyword

 3D-structure; Complete proteome; Direct protein sequencing; DNA damage; DNA repair; DNA replication; DNA-binding; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 178 AA 

Protein Sequence

Gene Ontology

 GO:0003697; F:single-stranded DNA binding; IDA:EcoCyc.
 GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
 GO:0006298; P:mismatch repair; TAS:EcoCyc.
 GO:0000725; P:recombinational repair; TAS:EcoCyc.
 GO:0009432; P:SOS response; TAS:EcoCyc. 

Interpro

 IPR012340; NA-bd_OB-fold.
 IPR000424; Primosome_PriB/ssb.
 IPR011344; ssDNA-bd. 

Pfam

 PF00436; SSB 

SMART

  

PROSITE

 PS50935; SSB 

PRINTS