UniProt Accession

 H7C1B9_HUMAN; H7C1B9 

Genbank Protein ID

 AC090941; AC090952; AC093496 

Genbank Nucleotide ID

  

Protein Name

 Sodium- and chloride-dependent taurine transporter 

Protein Synonyms/Alias

  

Gene Name

 SLC6A6 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
86	GPFLVRVKYLLTPRE	ubiquitination	[1, 2, 3]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Membrane; Reference proteome; Symport; Transmembrane; Transmembrane helix; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 95 AA 

Protein Sequence

Gene Ontology

 GO:0005887; C:integral to plasma membrane; IEA:InterPro.
 GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro.
 GO:0005369; F:taurine:sodium symporter activity; IEA:InterPro. 

Interpro

 IPR000175; Na/ntran_symport.
 IPR002434; Na/ntran_symport_taurine. 

Pfam

 PF00209; SNF 

SMART

  

PROSITE

 PS50267; NA_NEUROTRAN_SYMP_3 

PRINTS