UniProt Accession

 K7EIK4_HUMAN; K7EIK4 

Genbank Protein ID

 AC006538 

Genbank Nucleotide ID

  

Protein Name

 Thimet oligopeptidase 

Protein Synonyms/Alias

  

Gene Name

 THOP1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
147	QEGVLNSKVGMDYRS	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Hydrolase; Metal-binding; Metalloprotease; Protease; Reference proteome; Zinc. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 169 AA 

Protein Sequence

Gene Ontology

 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0004222; F:metalloendopeptidase activity; IEA:Compara.
 GO:0042277; F:peptide binding; IEA:Compara.
 GO:0007243; P:intracellular protein kinase cascade; IEA:Compara.
 GO:0006518; P:peptide metabolic process; IEA:Compara.
 GO:0006508; P:proteolysis; IEA:UniProtKB-KW. 

Interpro

 IPR024079; MetalloPept_cat_dom.
 IPR024077; Neurolysin/TOP_dom2.
 IPR001567; Pept_M3A_M3B. 

Pfam

 PF01432; Peptidase_M3 

SMART

  

PROSITE

  

PRINTS