UniProt Accession

 SH3L3_MOUSE; Q91VW3 

Genbank Protein ID

 AK003431; BC008110 

Genbank Nucleotide ID

 BAC25034.1; AAH08110.1 

Protein Name

 SH3 domain-binding glutamic acid-rich-like protein 3 

Protein Synonyms/Alias

  

Gene Name

 Sh3bgrl3 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
18	VTGSREIKSQQSEVT	acetylation	[1]
18	VTGSREIKSQQSEVT	ubiquitination	[2]

Reference

 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Could act as a modulator of glutaredoxin biological activity (By similarity). 

Sequence Annotation

 DOMAIN 1 93 Glutaredoxin.
 MOD_RES 2 2 N-acetylserine (By similarity).  

Keyword

 3D-structure; Acetylation; Complete proteome; Cytoplasm; Direct protein sequencing; Nucleus; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 93 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0009055; F:electron carrier activity; IEA:InterPro.
 GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
 GO:0045454; P:cell redox homeostasis; IEA:InterPro. 

Interpro

 IPR006993; Glut_rich_SH3-bd.
 IPR002109; Glutaredoxin.
 IPR012336; Thioredoxin-like_fold. 

Pfam

 PF04908; SH3BGR 

SMART

  

PROSITE

 PS51354; GLUTAREDOXIN_2 

PRINTS