CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030272
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Guanine monphosphate synthetase 
Protein Synonyms/Alias
 MCG6377, isoform CRA_a 
Gene Name
 Gmps 
Gene Synonyms/Alias
 mCG_6377 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
145SLFRGLQKEEIVLLTubiquitination[1]
165DKVADGFKVVARSGNubiquitination[1]
182AGIANESKKLYGVQFubiquitination[1]
183GIANESKKLYGVQFHubiquitination[1]
277IDNGFMRKRESQSVEubiquitination[1]
288QSVEEALKKLGIQVKubiquitination[1]
412GKVIEPLKDFHKDEVubiquitination[1]
457AEEPYICKDFPETNNubiquitination[1]
477ADFSASVKKPHTLLQubiquitination[1]
478DFSASVKKPHTLLQRubiquitination[1]
487HTLLQRVKACTTEEDubiquitination[1]
627FDRDPLQKQPSCQRSubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 693 AA 
Protein Sequence
MALCNGDSKP ENAGGDLKDG SHHYEGAVVI LDAGAQYGKV IDRRVRELFV QSEIFPLETP 60
AFAIKEQGFR AIIISGGPNS VYAEDAPWFD PAIFTIGKPI LGICYGMQMM NKVFGGTVHK 120
KSVREDGVFN ISMDNTCSLF RGLQKEEIVL LTHGDSVDKV ADGFKVVARS GNIVAGIANE 180
SKKLYGVQFH PEVGLTENGK VILKNFLYDI AGCSGNFTVQ NRELECIREI KEKVGTSKVL 240
VLLSGGVDST VCTALLNRAL NQDQVIAVHI DNGFMRKRES QSVEEALKKL GIQVKVINAA 300
HSFYNGTTTL PISDEDRTPR KRISKTLNMT TSPEEKRKII GDTFVKIANE VIGEMSLKPE 360
EVFLAQGTLR PDLIESASLV ASGKAELIKT HHNDTELIRK LREEGKVIEP LKDFHKDEVR 420
ILGRELDLPE ELVSRHPFPG PGLAIRVICA EEPYICKDFP ETNNILKIVA DFSASVKKPH 480
TLLQRVKACT TEEDQEKLMQ ITSLHSLNAF LLPIKTVGVQ GDCRSYSYVC GISSKDEPDW 540
ESLIFLARLI PRMCHNINRV VYIFGPPVKE PPTDVTPTFL TTGVLSTLRQ ADFEAHNILR 600
ESGFAGKISQ MPVILTPLHF DRDPLQKQPS CQRSVVIRTF ITSDFMTGVP ATPGNEIPVE 660
VVLKMVTEIK KIPGISRIMY DLTSKPPGTT EWE 693 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:InterPro.
 GO:0016462; F:pyrophosphatase activity; IEA:InterPro.
 GO:0006177; P:GMP biosynthetic process; IEA:InterPro. 
Interpro
 IPR017926; GATASE.
 IPR001674; GMP_synth_C.
 IPR004739; GMP_synth_N.
 IPR025777; GMPS_ATP_PPase_dom.
 IPR022310; NAD/GMP_synthase.
 IPR014729; Rossmann-like_a/b/a_fold. 
Pfam
 PF00117; GATase
 PF00958; GMP_synt_C
 PF02540; NAD_synthase 
SMART
  
PROSITE
 PS51273; GATASE_TYPE_1
 PS51553; GMPS_ATP_PPASE 
PRINTS