UniProt Accession

 KTR1_YEAST; P27810; D6W2G0 

Genbank Protein ID

 X62941; X94335; Z75007; BK006948 

Genbank Nucleotide ID

 CAA44713.1; CAA64021.1; CAA99296.1; DAA10876.1 

Protein Name

 Alpha-1,2 mannosyltransferase KTR1 

Protein Synonyms/Alias

  

Gene Name

 KTR1 

Gene Synonyms/Alias

 YOR099W; YOR3189W 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
10	KIMIPASKQPVYKKL	ubiquitination	[1]
45	RGSAPSPKYSTVLSS	ubiquitination	[1]
57	LSSGSGYKYSKVELP	acetylation	[2]
381	TKFYNINKLPKPAGW	acetylation	[2]

Reference

 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 

Functional Description

 Mannosyltransferase that transfers a mannose residue from GDP-mannose to a range of acceptors in vitro. 

Sequence Annotation

 REGION 35 68 Stem region (By similarity).
 REGION 69 393 Catalytic (By similarity).
 ACT_SITE 280 280 Nucleophile (Potential).
 CARBOHYD 120 120 N-linked (GlcNAc...) (Potential).  

Keyword

 Complete proteome; Glycoprotein; Glycosyltransferase; Golgi apparatus; Manganese; Membrane; Reference proteome; Signal-anchor; Transferase; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 393 AA 

Protein Sequence

Gene Ontology

 GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.
 GO:0005794; C:Golgi apparatus; IDA:SGD.
 GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0000026; F:alpha-1,2-mannosyltransferase activity; IDA:SGD.
 GO:0000032; P:cell wall mannoprotein biosynthetic process; IMP:SGD.
 GO:0006491; P:N-glycan processing; IGI:SGD.
 GO:0006493; P:protein O-linked glycosylation; IGI:SGD. 

Interpro

 IPR002685; Glyco_trans_15. 

Pfam

 PF01793; Glyco_transf_15 

SMART

  

PROSITE

  

PRINTS