CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032126
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Kinesin-associated protein 3 
Protein Synonyms/Alias
 cDNA FLJ53234, highly similar to Kinesin-associated protein 3 
Gene Name
 KIFAP3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
171ICEGNGLKMLMKRALubiquitination[1]
179MLMKRALKFKDPLLMubiquitination[1, 2]
187FKDPLLMKMIRNISQubiquitination[1]
347LIDLMHDKNNEIRKVubiquitination[1]
353DKNNEIRKVCDNTLDubiquitination[1]
371EYDEEWAKKIQSEKFubiquitination[1]
372YDEEWAKKIQSEKFRubiquitination[1]
377AKKIQSEKFRWHNSQubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 494 AA 
Protein Sequence
MRNKNIVHML VKALDRDNFE LLILVVSFLK KLSIFMENKN DMVEMDIVEK LVKMIPCEHE 60
DLLNITLRLL LNLSFDTGLR NKMVQVGLLP KLTALLGNDN YKQIAMCVLY HISMDDRFKS 120
MFAYTDCIPQ LMKMLFECSD ERIDLELISF CINLAANKRN VQLICEGNGL KMLMKRALKF 180
KDPLLMKMIR NISQHDGPTK NLFIDYVGDL AAQISNDEEE EFVIECLGTL ANLTIPDLDW 240
ELVLKEYKLV PYLKDKLKPG AAEDDLVLEV VIMIGTVSMD DSCAALLAKS GIIPALIELL 300
NAQQEDDEFV CQIIYVFYQM VFHQATRDVI IKETQAPAYL IDLMHDKNNE IRKVCDNTLD 360
IIAEYDEEWA KKIQSEKFRW HNSQWLEMVE SRQMDESEQY LYGDDRIEPY IHEGDILERP 420
DLFYNSDGLI ASEGAISPDF FNDYHLQNGD VVGQHSFPGS LGMDGFGQPV GILGRPATAY 480
GFRPDEPYYY GYGS 494 
Gene Ontology
 GO:0016939; C:kinesin II complex; IEA:Compara.
 GO:0007017; P:microtubule-based process; IEA:Compara.
 GO:0008285; P:negative regulation of cell proliferation; IEA:Compara.
 GO:0046587; P:positive regulation of calcium-dependent cell-cell adhesion; IEA:Compara.
 GO:0008104; P:protein localization; IEA:Compara. 
Interpro
 IPR011989; ARM-like.
 IPR016024; ARM-type_fold.
 IPR000225; Armadillo.
 IPR008658; KAP3. 
Pfam
  
SMART
 SM00185; ARM 
PROSITE
 PS50176; ARM_REPEAT 
PRINTS