Tag | Content |
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CPLM ID | CPLM-000673 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Beta-1,4-galactosyltransferase 5 |
Protein Synonyms/Alias | Beta-1,4-GalTase 5; Beta4Gal-T5; b4Gal-T5; Beta-1,4-GalT II; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 5; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 5 |
Gene Name | B4GALT5 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
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285 | LTVEQFRKINGFPNA | ubiquitination | [1] | 323 | RPEGDTGKYKSIPHH | ubiquitination | [1] |
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Reference | [1] Systematic and quantitative assessment of the ubiquitin-modified proteome. Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP. Mol Cell. 2011 Oct 21;44(2):325-40. [ PMID: 21906983] |
Functional Description | Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. |
Sequence Annotation | METAL 236 236 Manganese (By similarity). METAL 329 329 Manganese (By similarity). CARBOHYD 77 77 N-linked (GlcNAc...) (Potential). CARBOHYD 81 81 N-linked (GlcNAc...) (Potential). CARBOHYD 90 90 N-linked (GlcNAc...) (Potential). CARBOHYD 111 111 N-linked (GlcNAc...) (Potential). CARBOHYD 128 128 N-linked (GlcNAc...) (Potential). CARBOHYD 364 364 N-linked (GlcNAc...) (Potential). CARBOHYD 373 373 N-linked (GlcNAc...) (Potential). DISULFID 114 158 By similarity. DISULFID 229 248 By similarity. |
Keyword | Complete proteome; Disulfide bond; Glycoprotein; Glycosyltransferase; Golgi apparatus; Manganese; Membrane; Metal-binding; Polymorphism; Reference proteome; Signal-anchor; Transferase; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 388 AA |
Protein Sequence | MRARRGLLRL PRRSLLAALF FFSLSSSLLY FVYVAPGIVN TYLFMMQAQG ILIRDNVRTI 60 GAQVYEQVLR SAYAKRNSSV NDSDYPLDLN HSETFLQTTT FLPEDFTYFA NHTCPERLPS 120 MKGPIDINMS EIGMDYIHEL FSKDPTIKLG GHWKPSDCMP RWKVAILIPF RNRHEHLPVL 180 FRHLLPMLQR QRLQFAFYVV EQVGTQPFNR AMLFNVGFQE AMKDLDWDCL IFHDVDHIPE 240 SDRNYYGCGQ MPRHFATKLD KYMYLLPYTE FFGGVSGLTV EQFRKINGFP NAFWGWGGED 300 DDLWNRVQNA GYSVSRPEGD TGKYKSIPHH HRGEVQFLGR YALLRKSKER QGLDGLNNLN 360 YFANITYDAL YKNITVNLTP ELAQVNEY 388 |
Gene Ontology | GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell. GO:0000139; C:Golgi membrane; TAS:Reactome. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0008378; F:galactosyltransferase activity; TAS:ProtInc. GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. GO:0018146; P:keratan sulfate biosynthetic process; TAS:Reactome. GO:0016266; P:O-glycan processing; TAS:Reactome. GO:0043687; P:post-translational protein modification; TAS:Reactome. GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome. |
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