| Tag | Content |
|---|
| CPLM ID | CPLM-024488 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Tubulin alpha chain-like 3 |
Protein Synonyms/Alias | |
Gene Name | TUBAL3 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 278 | KCDPRLGKYMACCLL | ubiquitination | [1] |
|
Reference | [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW. Nature. 2013 Apr 18;496(7445):372-6. [ PMID: 23503661] |
Functional Description | Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). |
Sequence Annotation | NP_BIND 149 155 GTP (Potential). |
Keyword | Alternative splicing; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; GTP-binding; Microtubule; Nucleotide-binding; Polymorphism; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 446 AA |
Protein Sequence | MDQLENAKME HTNASFDTFF CETRAGKHVP RALFVDLEPT VIDGIRTGQH RSLFHPEQLL 60
SGKEDAANNY ARGRYSVGSE VIDLVLERTR KLAEQCGGLQ GFLIFRSFGG GTGSGFTSLL 120
MERLTGEYSR KTKLEFSVYP APRISTAVVE PYNSVLTTHS TTEHTDCTFM VDNEAVYDIC 180
HRKLGVECPS HASINRLVVQ VVSSITASLR FEGPLNVDLI EFQTNLVPYP RIHFPMTAFA 240
PIVSADKAYH EQFSVSDITT ACFESSNQLV KCDPRLGKYM ACCLLYRGDV VPKEVNAAIA 300
ATKSRHSVQF VDWCPTGFKV GINNRPPTVM PGGDLAKVHR SICMLSNTTA IVEAWARLDH 360
KFDLMYAKRA FLHWYLREGM EEAEFLEARE DLAALERDYE EVAQSF 406 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW. GO:0005874; C:microtubule; IEA:UniProtKB-KW. GO:0005525; F:GTP binding; IEA:UniProtKB-KW. GO:0003924; F:GTPase activity; IEA:InterPro. GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro. GO:0007017; P:microtubule-based process; IEA:InterPro. GO:0051258; P:protein polymerization; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |