CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028667
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 cAMP-dependent protein kinase type I-alpha regulatory subunit 
Protein Synonyms/Alias
  
Gene Name
 Prkar1a 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
70RQIQCLQKTGIRTDSubiquitination[1]
92PPPNPVVKGRRRRGAubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 171 AA 
Protein Sequence
MASGSMATSE EERSLRECEL YVQKHNIQAL LKDSIVQLCT TRPERPMAFL REYFERLEKE 60
EARQIQCLQK TGIRTDSRED EISPPPPNPV VKGRRRRGAI SAEVYTEEDA ASYVRKVIPK 120
DYKTMAALAK AIEKNVLFSH LDDNERSDIF DAMFPVSFIA GETVIQQGKG C 171 
Gene Ontology
 GO:0005737; C:cytoplasm; TAS:MGI.
 GO:0031594; C:neuromuscular junction; IDA:MGI.
 GO:0008603; F:cAMP-dependent protein kinase regulator activity; IDA:MGI.
 GO:0060038; P:cardiac muscle cell proliferation; IMP:MGI.
 GO:0001707; P:mesoderm formation; IMP:MGI.
 GO:0006469; P:negative regulation of protein kinase activity; IMP:MGI.
 GO:0009887; P:organ morphogenesis; TAS:MGI.
 GO:0006468; P:protein phosphorylation; TAS:MGI.
 GO:0045214; P:sarcomere organization; IMP:MGI.
 GO:0007165; P:signal transduction; IEA:InterPro. 
Interpro
 IPR003117; cAMP_dep_PK_reg_su_I/II_a/b.
 IPR018490; cNMP-bd-like.
 IPR000595; cNMP-bd_dom.
 IPR014710; RmlC-like_jellyroll. 
Pfam
 PF02197; RIIa 
SMART
 SM00394; RIIa 
PROSITE
 PS50042; CNMP_BINDING_3 
PRINTS