CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-018608
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 N-terminal EF-hand calcium-binding protein 2 
Protein Synonyms/Alias
 EF-hand calcium-binding protein 2; Neuronal calcium-binding protein 2 
Gene Name
 Necab2 
Gene Synonyms/Alias
 Efcbp2 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
156KAMGYTKKVYEGGSNubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
 DOMAIN 63 98 EF-hand 1.
 DOMAIN 97 132 EF-hand 2.
 DOMAIN 287 377 ABM.  
Keyword
 Alternative splicing; Calcium; Coiled coil; Complete proteome; Cytoplasm; Metal-binding; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 389 AA 
Protein Sequence
MCERAARLCR AGAHRLLREP PPQGRALGGL LRWVGARMGE PRAPLVPDIP SADPGPGPAA 60
SRGGTAVILD IFRRADKNDD GKLSLEEFQL FFADGVLNEK ELEGLFHTID SDNTNHVDTK 120
ELCDYFVEHM GDYEDVLASL ETLNHSVLKA MGYTKKVYEG GSNVDQFVTR FLLKETANQI 180
QSLLSSVESA VEAIEEQTSQ IRQDHCKPSH AVNESRYGGP TPPYIPNHKL VAPEPMKSLP 240
VATGEPKEDG LEGQISRLAE LIGRLESKTL SFDLQQRLSD EEGTNMHLQL VRQEMAVCPE 300
QLSEFLDSLR QYLRSTAEER NCFHVAAVRM ADGLTFVIYE FWETEEEWKR HLQSPVCKAF 360
RHVKVDTLSQ PEALSQISVP AAWCTSGRD 389 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005509; F:calcium ion binding; IEA:InterPro. 
Interpro
 IPR007138; Antibiotic_mOase.
 IPR011008; Dimeric_a/b-barrel.
 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom. 
Pfam
 PF03992; ABM
 PF13499; EF_hand_5 
SMART
 SM00054; EFh 
PROSITE
 PS00018; EF_HAND_1
 PS50222; EF_HAND_2 
PRINTS